N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2-diphenylacetamide

Base Information

Chemical Name:N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2-diphenylacetamide
CAS No.:30488-64-3
Molecular Formula:C24H25 N O3
Molecular Weight:375.4602
Hs Code.:
Mol file:30488-64-3.mol

Synonyms:Acetamide,N-(3,4-dimethoxyphenethyl)-2,2-diphenyl- (8CI); Diphenylacetic acidN-[2-(3,4-dimethoxyphenyl)ethyl]amide; NSC 149616

Suppliers and Price of N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2-diphenylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2-diphenylacetamide

Chemical Property:

Vapor Pressure:1.12E-13mmHg at 25°C
Boiling Point:585.1°Cat760mmHg
Flash Point:307.7°C
Density:1.124g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2-diphenylacetamide

There total 5 articles about N-[2-(3,4-dimethoxyphenyl)ethyl]-2,2-diphenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 117-34-0
2,2-diphenylacetic acid

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 30488-64-3
N-(2-(3,4-dimethoxyphenyl)ethyl)-2,2-diphenylacetamide

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/cmdc.201300332

Reference yield:

: 1871-76-7
diphenylacetic acid chloride

: 120-20-7
2-(3,4-dimethoxyphenyl)-ethylamine

: 30488-64-3
N-(2-(3,4-dimethoxyphenyl)ethyl)-2,2-diphenylacetamide

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 48h;
DOI:10.1021/ja042913p

Reference yield:

: 117-34-0
2,2-diphenylacetic acid

: 30488-64-3
N-(2-(3,4-dimethoxyphenyl)ethyl)-2,2-diphenylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride; DMF / CH₂Cl₂ / 12 h

2: Et₃N; 4-N,N-dimethylaminopyridine / CH₂Cl₂ / 48 h / 0 - 20 °C

With dmap; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/ja042913p