Quinoline, 2-bromo-3-fluoro-5,7-dimethyl-

Base Information

Chemical Name:Quinoline, 2-bromo-3-fluoro-5,7-dimethyl-
CAS No.:834884-05-8
Molecular Formula:C11H9BrFN
Molecular Weight:
Hs Code.:
DSSTox Substance ID:DTXSID90479741
Nikkaji Number:J2.136.905E
Wikidata:Q82313929

Synonyms:834884-05-8;Quinoline, 2-bromo-3-fluoro-5,7-dimethyl-;DTXSID90479741;AKOS024263624

Suppliers and Price of Quinoline, 2-bromo-3-fluoro-5,7-dimethyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Quinoline, 2-bromo-3-fluoro-5,7-dimethyl-

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:252.99024
Heavy Atom Count:14
Complexity:212

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C=C(C(=NC2=C1)Br)F)C

Technology Process of Quinoline, 2-bromo-3-fluoro-5,7-dimethyl-

There total 3 articles about Quinoline, 2-bromo-3-fluoro-5,7-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 834883-97-5
3-fluoro-5,7-dimethylquinol-2(1H)-one

: 834884-05-8
2-bromo-3-fluoro-5,7-dimethylquinoline

Guidance literature:: With phosphorus(V) oxybromide; In various solvent(s); for 2h; Heating;
DOI:10.1016/j.tet.2004.10.053

Reference yield:

: N-(3,5-dimethyl-phenyl)-2-fluoro-3-methoxy-acrylamide

: 834884-05-8
2-bromo-3-fluoro-5,7-dimethylquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 81.8 g / hydrochloric acid / 5 h / 50 °C

2: 82 percent / phosphoric tribromide / various solvent(s) / 2 h / Heating

With hydrogenchloride; phosphorus(V) oxybromide; In various solvent(s);
DOI:10.1016/j.tet.2004.10.053

Reference yield:

: 108-69-0
3,5-dimethylaminoaniline

: 834884-05-8
2-bromo-3-fluoro-5,7-dimethylquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: butyllithium / tetrahydrofuran; hexane / 1 h / 25 °C

2: 81.8 g / hydrochloric acid / 5 h / 50 °C

3: 82 percent / phosphoric tribromide / various solvent(s) / 2 h / Heating

With hydrogenchloride; n-butyllithium; phosphorus(V) oxybromide; In tetrahydrofuran; hexane;
DOI:10.1016/j.tet.2004.10.053