2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Base Information

Chemical Name:2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
CAS No.:24806-96-0
Molecular Formula:C₇H₁₂N₄O₄
Molecular Weight:216.197
Hs Code.:
NSC Number:133122
DSSTox Substance ID:DTXSID60947720
Mol file:24806-96-0.mol

Synonyms:686299-18-3;2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol;24806-96-0;NSC133122;DTXSID60947720;NSC-133122;1-Pentofuranosyl-1,2-dihydro-3H-1,2,4-triazol-3-imine

Suppliers and Price of 2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Chemical Property:

Vapor Pressure:1.6E-15mmHg at 25°C
Boiling Point:605.7°Cat760mmHg
Flash Point:320.1°C
Density:2.08g/cm³
XLogP3:-2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:216.08585488
Heavy Atom Count:15
Complexity:231

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=NC(=NN1C2C(C(C(O2)CO)O)O)N

Technology Process of 2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

There total 6 articles about 2-(3-Amino-1H-1,2,4-triazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 24806-95-9
3-Nitro-1-β-D-ribofuranosyl-1,2,4-triazol

: 24806-96-0,686299-18-3
3-Amino-1-(β-D-ribofuranosyl)-1.2.4-triazol

Guidance literature:: With hydrazine; In water; at 20 ℃; for 0.5h;
DOI:10.1016/j.bmcl.2007.03.018

Reference yield:

: C₂₈H₂₄N₄O₇

: 24806-96-0,686299-18-3
3-Amino-1-(β-D-ribofuranosyl)-1.2.4-triazol

Guidance literature:: With ammonia; In methanol; at 50 ℃; for 16h;
DOI:10.1021/jo061885l

Reference yield:

: 6974-32-9
1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose

: 24806-96-0,686299-18-3
3-Amino-1-(β-D-ribofuranosyl)-1.2.4-triazol

Guidance literature:: Multi-step reaction with 2 steps

1: N,O-bis(trimethylsilyl)acetamide; trimethylsilyl triflate / acetonitrile / 0.08 h / 130 °C / microwave irradiation

2: NH₃ / methanol / 16 h / 50 °C

With N,O-bis-(trimethylsilyl)-acetamide; trimethylsilyl trifluoromethanesulfonate; ammonia; In methanol; acetonitrile; 1: Vorbrueggen glycosylation;
DOI:10.1021/jo061885l