tert-butyl (3-bromo-4-(trifluoromethoxy)phenyl)carbamate

Base Information

Chemical Name:tert-butyl (3-bromo-4-(trifluoromethoxy)phenyl)carbamate
CAS No.:839715-01-4
Molecular Formula:C12H13BrF3NO3
Molecular Weight:356.139
Hs Code.:
Mol file:839715-01-4.mol

Synonyms:(3-bromo-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester;

Suppliers and Price of tert-butyl (3-bromo-4-(trifluoromethoxy)phenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
tert-butyl3-bromo-4-(trifluoromethoxy)phenylcarbamate 95
10g
$ 1467.00

American Custom Chemicals Corporation
TERT-BUTYL 3-BROMO-4-(TRIFLUOROMETHOXY)PHENYLCARBAMATE 95.00%
5MG
$ 504.08

Total 3 raw suppliers

Chemical Property of tert-butyl (3-bromo-4-(trifluoromethoxy)phenyl)carbamate

Chemical Property:

PSA：47.56000
LogP:4.76770

Purity/Quality:

99% ^*data from raw suppliers

tert-butyl3-bromo-4-(trifluoromethoxy)phenylcarbamate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyl (3-bromo-4-(trifluoromethoxy)phenyl)carbamate

There total 1 articles about tert-butyl (3-bromo-4-(trifluoromethoxy)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 191602-54-7
3-bromo-4-(trifluoromethoxy)aniline

: 839715-01-4
(3-bromo-4-trifluoromethoxyphenyl)carbamic acid tert-butyl ester

Guidance literature:: In 1,4-dioxane; at 80 ℃;
DOI:10.1021/jm9007328

Reference yield: 37.0%

: 839715-01-4
(3-bromo-4-trifluoromethoxyphenyl)carbamic acid tert-butyl ester

: 720702-41-0
(1-methyl-1H-pyrazol-5-yl)boronic acid

: 839715-02-5
[3-(2-methyl-2H-pyrazol-3-yl)-4-trifluoromethoxyphenyl]carbamic acid tert-butyl ester

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 80 ℃; Inert atmosphere;
DOI:10.1021/jm9007328

Reference yield:

: 839715-01-4
(3-bromo-4-trifluoromethoxyphenyl)carbamic acid tert-butyl ester

: 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-trifluoromethoxy-phenyl]-3-(4-chlorophenyl)urea

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / Dimethyl ether; water / 20 - 80 °C

2.1: dichloromethane / 0.33 h / 20 °C

3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C / pH 7 - 8

3.2: 20 °C

With sodium carbonate; N-ethyl-N,N-diisopropylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In Dimethyl ether; dichloromethane; water;