Ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate

Base Information

Chemical Name:Ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate
CAS No.:35085-34-8
Molecular Formula:C15H22ClO5P
Molecular Weight:348.763
Hs Code.:
NSC Number:112266
DSSTox Substance ID:DTXSID20296862

Synonyms:35085-34-8;NSC112266;SCHEMBL7342541;DTXSID20296862;NSC-112266;ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate

Suppliers and Price of Ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate

Chemical Property:

Vapor Pressure:4.51E-08mmHg at 25°C
Boiling Point:443.8°Cat760mmHg
Flash Point:360.1°C
Density:1.2g/cm³
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:348.0893385
Heavy Atom Count:22
Complexity:372

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(CC1=CC=C(C=C1)Cl)P(=O)(OCC)OCC

Technology Process of Ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate

There total 3 articles about Ethyl 3-(4-chlorophenyl)-2-(diethoxyphosphoryl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 35085-34-8
ethyl 2-(diethoxyphosphoryl)-3-(4-chlorophenyl)propanoate

Guidance literature:: With hydrogenchloride; In N-methyl-acetamide;

Reference yield:

: 867-13-0
diethoxyphosphoryl-acetic acid ethyl ester

: 622-95-7
4-chlorobenzyl bromide

: 35085-34-8
ethyl 2-(diethoxyphosphoryl)-3-(4-chlorophenyl)propanoate

Guidance literature:: diethoxyphosphoryl-acetic acid ethyl ester; With sodium hydride; In 1,2-dimethoxyethane; at 25 ℃; for 2h;

4-chlorobenzyl bromide; In 1,2-dimethoxyethane; at 60 ℃; for 2h;
DOI:10.1021/acs.jmedchem.5b01775