Ethanone, 1-[2-hydroxy-4,6-bis(methoxymethoxy)-3-(3-methyl-2-butenyl)phenyl]-

Base Information

• Chemical Name: Ethanone, 1-[2-hydroxy-4,6-bis(methoxymethoxy)-3-(3-methyl-2-butenyl)phenyl]-
• CAS No.: 84092-45-5
• Molecular Formula: C17H24O6
• Molecular Weight: 324.374
• Mol file: 84092-45-5.mol

Synonyms:2-hydroxy-4,6-dimethoxymethoxy-5-C-prenyl-acetophenone;2-hydroxy-4,6-di(methoxymethoxy)-3-C-prenylacetophenone;1-[2-Hydroxy-4,6-bis-methoxymethoxy-3-(3-methyl-but-2-enyl)-phenyl]-ethanone;2',4'-bis(methoxymethoxy)-5'-(3'',3''-dimethylallyl)-6'-hydroxyacetophenone;4,6-dimethoxymethoxy-3-(3,3-dimethylallyl)-2-hydroxyacetophenone;2-hydroxy-4,6-di-(methoxymethoxy)-3-C-prenylacetophenone;4',6'-dimethoxymethoxy-3'-(3,3-dimethylallyl)-2'-hydroxy-acetophenone;

Chemical Property of Ethanone, 1-[2-hydroxy-4,6-bis(methoxymethoxy)-3-(3-methyl-2-butenyl)phenyl]-

Chemical Property:

• Boiling Point: 472.9±45.0 °C(Predicted)
• PSA: 74.22000
• Density: 1.122±0.06 g/cm3(Predicted)
• LogP: 3.06890

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-[2-hydroxy-4,6-bis(methoxymethoxy)-3-(3-methyl-2-butenyl)phenyl]-

There total 10 articles about Ethanone, 1-[2-hydroxy-4,6-bis(methoxymethoxy)-3-(3-methyl-2-butenyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone (27364-71-2) + chloromethyl methyl ether (107-30-2) → 2',4'-bis(methoxymethoxy)-5'-(3,3-dimethylallyl)-6'-hydroxyacetophenone (84092-45-5)

Guidance literature:

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone; With N-ethyl-N,N-diisopropylamine; In acetone; for 0.166667h; Cooling with ice;

chloromethyl methyl ether; In acetone; at 60 ℃; for 2h; Inert atmosphere; Cooling with ice;

Reference yield: 82.8%

→ 3-(3-methylbutyl)-2-hydroxy-4,6-bis(methoxymethoxy)acetophenone (112772-56-2) + 2',4'-bis(methoxymethoxy)-5'-(3,3-dimethylallyl)-6'-hydroxyacetophenone (84092-45-5)

Guidance literature:

Reference yield: 45.0%

bromethyl methyl ether (13057-17-5) + 2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone (27364-71-2) → 2',4'-bis(methoxymethoxy)-5'-(3,3-dimethylallyl)-6'-hydroxyacetophenone (84092-45-5)

Guidance literature:

With potassium carbonate; In acetone; for 3h; Reflux;

DOI:10.1021/np800188b

upstream raw materials:

2'-hydroxy-4',6'-bis(methoxymethoxy)acetophenone

prenyl bromide

2',4',6'-trihydroxy-3'-(3-methyl-2-butenyl)acetophenone

chloromethyl methyl ether

Downstream raw materials:

2-hydroxy-4,4',6-tri(methoxymethoxy)-3-(3,3-dimethylallyl)chalcone

5'-(3,3-dimethylallyl)-6'-hydroxy-3,4,2',4'-tetrakis(methoxymethoxy)chalcone

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-8-(3-methyl-but-2-enyl)-chroman-4-one

5,7,4'-trimethoxymethoxy-8-(3,3-dimethylallyl)-flavanone