Diethyl (2-methoxyethyl)methylpropanedioate

Base Information

• Chemical Name: Diethyl (2-methoxyethyl)methylpropanedioate
• CAS No.: 20721-76-0
• Molecular Formula: C11H20O5
• Molecular Weight: 232.2735
• DSSTox Substance ID: DTXSID30174788
• Nikkaji Number: J1.609.076J
• Wikidata: Q83044932
• Mol file: 20721-76-0.mol

Synonyms:20721-76-0;DIETHYL (2-METHOXYETHYL)METHYLPROPANEDIOATE;DTXSID30174788;Methyl(2-methoxyethyl)propanedioic acid diethyl ester

Chemical Property of Diethyl (2-methoxyethyl)methylpropanedioate

Chemical Property:

• Vapor Pressure: 0.00303mmHg at 25°C
• Boiling Point: 284.1°Cat760mmHg
• Flash Point: 118.6°C
• Density: 1.039g/cm³
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 9
• Exact Mass: 232.13107373
• Heavy Atom Count: 16
• Complexity: 219

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(C)(CCOC)C(=O)OCC

Technology Process of Diethyl (2-methoxyethyl)methylpropanedioate

There total 1 articles about Diethyl (2-methoxyethyl)methylpropanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Diethyl methylmalonate (609-08-5) + 2-Bromoethyl methyl ether (6482-24-2) → β-Methoxyethyl-methyl-malonsaeurediethylester (20721-76-0)

Guidance literature:

With ethanol; sodium ethanolate;

Reference yield:

β-Methoxyethyl-methyl-malonsaeurediethylester (20721-76-0) → 4-methoxy-2-methyl-butyric acid anilide

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous methanolic KOH / anschliessendes Decarboxylieren

2: thionyl chloride / anschliessend mit Anilin

With potassium hydroxide; thionyl chloride;

DOI:10.1002/hlca.19440270166

upstream raw materials:

Diethyl methylmalonate

2-Bromoethyl methyl ether