2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol

Base Information

Chemical Name:2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol
CAS No.:84203-53-2
Molecular Formula:C18H26N2O
Molecular Weight:286.41200
Hs Code.:
DSSTox Substance ID:DTXSID70579455
Wikidata:Q82469978

Synonyms:84203-53-2;2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol;SCHEMBL10786930;DTXSID70579455;LQRMSNRZRPDAOE-UHFFFAOYSA-N;4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methylimidazole

Suppliers and Price of 2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol

Chemical Property:

PSA：48.91000
LogP:4.68570
XLogP3:5.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:286.204513457
Heavy Atom Count:21
Complexity:331

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=CN1)C2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C

Technology Process of 2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol

There total 4 articles about 2,6-Di-tert-butyl-4-(5-methyl-1H-imidazol-4-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.1%

: 84203-44-1
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methyl-2-thioxo-4-imidazoline

: 84203-53-2
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methylimidazole

Guidance literature:: nickel; In ethanol; for 1h; Heating;
DOI:10.1248/cpb.32.152

Reference yield:

: 17055-13-9
4-(2-bromopropionyl)-2,6-di-tert-butylphenol

: 84203-53-2
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methylimidazole

Guidance literature:: Multi-step reaction with 4 steps

1: sodium azide / H₂O; acetone / 1 h / Ambient temperature

2: H₂, HCl / Pd-C / methanol

3: 57.8 percent / HCl / H₂O; ethanol / 1.5h, r.t., 2h, reflux

4: 74.1 percent / Raney nickel / ethanol / 1 h / Heating

With hydrogenchloride; sodium azide; hydrogen; palladium on activated charcoal; nickel; In methanol; ethanol; water; acetone;
DOI:10.1248/cpb.32.152

Reference yield:

: 2-Azido-1-(3,5-di-tert-butyl-4-hydroxy-phenyl)-propan-1-one

: 84203-53-2
4-(3,5-di-tert-butyl-4-hydroxyphenyl)-5-methylimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: H₂, HCl / Pd-C / methanol

2: 57.8 percent / HCl / H₂O; ethanol / 1.5h, r.t., 2h, reflux

3: 74.1 percent / Raney nickel / ethanol / 1 h / Heating

With hydrogenchloride; hydrogen; palladium on activated charcoal; nickel; In methanol; ethanol; water;
DOI:10.1248/cpb.32.152