(1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine

Base Information

Chemical Name:(1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine
CAS No.:84235-33-6
Molecular Formula:C7H13N
Molecular Weight:111.187
Hs Code.:
DSSTox Substance ID:DTXSID30433660
Nikkaji Number:J215.861B
Wikidata:Q82247858
ChEMBL ID:CHEMBL3736187

Synonyms:(1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine;84235-33-6;SCHEMBL353876;CHEMBL3736187;DTXSID30433660;(1beta,2beta,4beta)-2-Aminonorbornane;CS-0119831

Suppliers and Price of (1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ACHEMBLOCK
(1S,2S,4R)-bicyclo[2.2.1]heptan-2-amine 97%
250MG
$ 290.00

Total 5 raw suppliers

Chemical Property of (1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine

Chemical Property:

PSA：26.02000
LogP:1.83400
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:111.104799419
Heavy Atom Count:8
Complexity:101

Purity/Quality:

97% ^*data from raw suppliers

(1S,2S,4R)-bicyclo[2.2.1]heptan-2-amine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2CC1CC2N
Isomeric SMILES:C1C[C@H]2C[C@@H]1C[C@@H]2N

Technology Process of (1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine

There total 16 articles about (1S,2S,4R)-Bicyclo[2.2.1]heptan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1389327-48-3
N-((1R,2R,4S)-bicyclo[2.2.1]heptan-2-yl)-4-(trifluoromethyl)benzamide

: 822-98-0,7242-92-4,31002-73-0,84235-33-6,84235-34-7,111137-34-9,121055-07-0,126752-99-6,130463-97-7
(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamine

Guidance literature:: With hydrogenchloride; at 120 ℃; for 72h; optical yield given as %ee; Inert atmosphere;
DOI:10.1021/ja3052848

Reference yield:

: 342029-20-3
C₇H₁₁BrZn

: 822-98-0,7242-92-4,31002-73-0,84235-33-6,84235-34-7,111137-34-9,121055-07-0,126752-99-6,130463-97-7
(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamine

: (1R,2R,4S)-2-aminobicyclo<2.2.1>heptane hydrochloride

Guidance literature:: C₇H₁₁BrZn; With 3,3’-di-tert-butyl oxaziridine; In diethyl ether; at 20 ℃; for 6h; Inert atmosphere;

With hydrogenchloride; In water; at 0 ℃; Overall yield = 61 %;
DOI:10.1021/acs.orglett.8b03734

Reference yield:

: (1S,2S,4R)-bicyclo[2.2.1]heptan-2-amine

: 822-98-0,7242-92-4,31002-73-0,84235-33-6,84235-34-7,111137-34-9,121055-07-0,126752-99-6,130463-97-7
(1R,2R,4S)-bicyclo[2.2.1]hept-2-ylamine

: 84235-33-6
(+)-(1S,2S,4R)-2-norbornylamine

Guidance literature:: With chiral stationary phase including isopropyl-functionalized CF₆; In methanol; acetic acid; triethylamine; acetonitrile; at 20 ℃; Purification / work up;