4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol

Base Information

Chemical Name:4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol
CAS No.:84292-46-6
Molecular Formula:C15H13N3O
Molecular Weight:251.288
Hs Code.:
ChEMBL ID:CHEMBL3427196
DSSTox Substance ID:DTXSID40515729
Wikidata:Q82376776

Synonyms:84292-46-6;4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol;CHEMBL3427196;DTXSID40515729

Suppliers and Price of 4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:251.105862047
Heavy Atom Count:19
Complexity:285

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=NN1C2=CC=C(C=C2)O)C3=CC=CC=C3

Technology Process of 4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol

There total 7 articles about 4-(5-Methyl-4-phenyl-1H-1,2,3-triazol-1-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 84292-44-4
4-(5-methyl-4-phenyl-1H-1,2,3-triazol-1-yl)benzenamine

: 84292-46-6
1-(4-Hydroxyphenyl)-4-phenyl-5-methyl-1,2,3-triazole

Guidance literature:: With sulfuric acid; sodium nitrite; In water; at 80 - 90 ℃; for 0.5h;

Reference yield: 51.0%

: 1-(4-methoxyphenyl)-5-methyl-4-phenyl-1H-1,2,3-triazole

: 84292-46-6
1-(4-Hydroxyphenyl)-4-phenyl-5-methyl-1,2,3-triazole

Guidance literature:: With boron tribromide; In dichloromethane; at -50 - 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2015.02.049

Reference yield:

: 1516-60-5
4-nitrophenyl azide

: 84292-46-6
1-(4-Hydroxyphenyl)-4-phenyl-5-methyl-1,2,3-triazole

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / EtONa / ethanol / 24 h / Ambient temperature

2: 94 percent / SnCl₂*2H₂O, 6 M HCl / 3 h / Heating

3: 60 percent / NaNO₂, conc. H₂SO₄ / H₂O / 0.5 h / 80 - 90 °C

With hydrogenchloride; sulfuric acid; sodium ethanolate; tin(ll) chloride; sodium nitrite; In ethanol; water;