2-(Naphthalen-2-ylcarbonyl)benzoic acid

Base Information

• Chemical Name: 2-(Naphthalen-2-ylcarbonyl)benzoic acid
• CAS No.: 38119-03-8
• Molecular Formula: C18H12 O3
• Molecular Weight: 276.291
• NSC Number: 74889
• DSSTox Substance ID: DTXSID30291323
• Nikkaji Number: J917.408G
• Wikidata: Q82029247
• Mol file: 38119-03-8.mol

Synonyms:38119-03-8;Benzoic acid,2-(2-naphthalenylcarbonyl)-;2-(naphthalene-2-carbonyl)benzoic acid;2-(naphthalen-2-ylcarbonyl)benzoic acid;2-Naphthoylbenzoicacid;2-(2-Naphthoyl)benzoic acid;2-(2-naphthylcarbonyl)benzoic acid;NSC74889;SCHEMBL7828608;2-(2-Naphthoyl)benzoic acid #;DTXSID30291323;BGLNPRRTOGJLIE-UHFFFAOYSA-N;MFCD00046492;NSC-74889;AKOS024358722;AS-84387;SY293300;Benzoic acid, 2-(2-naphthalenylcarbonyl)-;E77758

Chemical Property of 2-(Naphthalen-2-ylcarbonyl)benzoic acid

Chemical Property:

• Vapor Pressure: 6.96E-12mmHg at 25°C
• Boiling Point: 525.8°Cat760mmHg
• Flash Point: 285.9°C
• Density: 1.289g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 276.078644241
• Heavy Atom Count: 21
• Complexity: 403

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=C(C=CC2=C1)C(=O)C3=CC=CC=C3C(=O)O

Technology Process of 2-(Naphthalen-2-ylcarbonyl)benzoic acid

There total 10 articles about 2-(Naphthalen-2-ylcarbonyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phthalic anhydride (85-44-9) + naphthalene (91-20-3,71998-51-1,72931-45-4) → 2-[2]naphthoyl-benzoic acid (38119-03-8) + 2-(naphthalene-1-carbonyl)-benzoic acid (5018-87-1)

Guidance literature:

With aluminium trichloride; 1,1,2,2-tetrachloroethane;

DOI:10.1007/BF00899425

Reference yield:

3,4-dihydronaphthalene-1(2H)-one (529-34-0) → 2-[2]naphthoyl-benzoic acid (38119-03-8) + 2-(naphthalene-1-carbonyl)-benzoic acid (5018-87-1)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium permanganate; potassium hydroxide / water / Reflux

2: sulfuryl dichloride

3: aluminum (III) chloride

With aluminum (III) chloride; potassium permanganate; sulfuryl dichloride; potassium hydroxide; In water; 3: Friedel-Crafts condensation;

DOI:10.1039/c0ob01107j

Reference yield:

4-Phenylbutyric acid (1821-12-1) → 2-[2]naphthoyl-benzoic acid (38119-03-8) + 2-(naphthalene-1-carbonyl)-benzoic acid (5018-87-1)

Guidance literature:

Multi-step reaction with 4 steps

1: methanesulfonic acid / 0.5 h / 90 °C / Inert atmosphere

2: potassium permanganate; potassium hydroxide / water / Reflux

3: sulfuryl dichloride

4: aluminum (III) chloride

With aluminum (III) chloride; potassium permanganate; sulfuryl dichloride; methanesulfonic acid; potassium hydroxide; In water; 4: Friedel-Crafts condensation;

DOI:10.1039/c0ob01107j

upstream raw materials:

phthalic anhydride

naphthalene

2-naphthalenylmagnesium bromide

benzene

Downstream raw materials:

benz[a]anthracene-7,12-dione

2-(Naphthalene-2-yl)methylbenzoic acid

(R)-2-(1-(naphthalen-2-yl)ethyl)benzoic acid

(S)-2-(1-phenylethyl)naphthalene