N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide

Base Information

Chemical Name:N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide
CAS No.:84858-16-2
Molecular Formula:C18H17N3O3
Molecular Weight:323.351
Hs Code.:
DSSTox Substance ID:DTXSID90517354

Synonyms:84858-16-2;N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide;N-[1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl]formamide;DTXSID90517354

Suppliers and Price of N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:323.12699141
Heavy Atom Count:24
Complexity:461

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=C(C2=C(N1C)C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3)NC=O

Technology Process of N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide

There total 4 articles about N-(1-(1-Methyl-5-nitro-3-phenyl-1H-indol-2-yl)ethyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 84858-16-2
1-Methyl-2-(1'-formylaminoethyl)-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 4 steps

2: 78 percent / AcOH, conc. HCl / 3 h / 100 °C

3: 92 percent / 50percent aq. KOH / acetone / 1 h / 20 °C

4: 50 percent / 7 h / 170 - 180 °C

With hydrogenchloride; potassium hydroxide; acetic acid; In acetone;
DOI:10.1007/BF00765129

Reference yield:

: 89141-67-3
2-Acetyl-3-phenyl-5-nitroindole

: 84858-16-2
1-Methyl-2-(1'-formylaminoethyl)-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / 50percent aq. KOH / acetone / 1 h / 20 °C

2: 50 percent / 7 h / 170 - 180 °C

With potassium hydroxide; In acetone;
DOI:10.1007/BF00765129

Reference yield:

: 84852-64-2
1-Phenylbutane-2,3-dione 2-(p-nitrophenylhydrazone)

: 84858-16-2
1-Methyl-2-(1'-formylaminoethyl)-3-phenyl-5-nitroindole

Guidance literature:: Multi-step reaction with 3 steps

1: 78 percent / AcOH, conc. HCl / 3 h / 100 °C

2: 92 percent / 50percent aq. KOH / acetone / 1 h / 20 °C

3: 50 percent / 7 h / 170 - 180 °C

With hydrogenchloride; potassium hydroxide; acetic acid; In acetone;
DOI:10.1007/BF00765129