Technology Process of Benzenepropanoic acid, a-hydroxy-,6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester, [2aR-[2aa,4b,4ab,6b,9a(S*),11a,12a,12aa,12ba]]- (9CI)
There total 3 articles about Benzenepropanoic acid, a-hydroxy-,6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester, [2aR-[2aa,4b,4ab,6b,9a(S*),11a,12a,12aa,12ba]]- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid; zinc;
In
methanol;
at 40 ℃;
for 5h;
Yield given;
DOI:10.1021/jm00107a042
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dipyridyl carbonate, 4-(dimethylamino)pyridine / toluene / 48 h / 70 °C
2: Zn, AcOH / methanol / 5 h / 40 °C
With
dmap; 2,2'-dipyridyl carbonate; acetic acid; zinc;
In
methanol; toluene;
DOI:10.1021/jm00107a042
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dipyridyl carbonate, 4-(dimethylamino)pyridine / toluene / 48 h / 70 °C
2: Zn, AcOH / methanol / 5 h / 40 °C
With
dmap; 2,2'-dipyridyl carbonate; acetic acid; zinc;
In
methanol; toluene;
DOI:10.1021/jm00107a042
