Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Base Information

Chemical Name:Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester
CAS No.:82585-97-5
Molecular Formula:C16H15Cl2N5O2
Molecular Weight:380.2286
Hs Code.:
NSC Number:341931
DSSTox Substance ID:DTXSID80231895
Wikidata:Q83112890
ChEMBL ID:CHEMBL9699

Synonyms:NSC341931;82585-97-5;Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester;CHEMBL9699;SCHEMBL11006975;DTXSID80231895;NSC 341931;NSC-341931;Ethyl (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)carbamate;ethyl N-[5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-yl]carbamate;NCI60_003031;(5-AMINO-3-(2,2-DIHYDRIPYRIDO[3,4-B]PYRAZIN-7-YL)CARBAMIC ACID, ETHYL ESTER;Carbamic acid,4-dichlorophenyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-yl]-, ethyl ester;N-[5-Amino-3-(2,4-dichlorophenyl)(1,2-dihydropyridino[5,4-b]pyrazin-7-yl)]ethoxycarboxamide

Suppliers and Price of Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

Chemical Property:

Vapor Pressure:3.83E-11mmHg at 25°C
Boiling Point:525.7°Cat760mmHg
Flash Point:271.7°C
Density:1.57g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:379.0602801
Heavy Atom Count:25
Complexity:521

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)NC1=NC(=C2C(=C1)NCC(=N2)C3=C(C=C(C=C3)Cl)Cl)N

Technology Process of Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester

There total 4 articles about Carbamic acid, (5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido(3,4-b)pyrazin-7-yl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 82585-36-2
α-amino-2,4-dichloroacetophenone oxime

: 82585-97-5
ethyl 5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-ylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / Et₃N / ethanol / 2.5 h / 75 °C

2: 64 percent / H₂ / Raney nickel / ethanol / 24 h / 760 Torr / Ambient temperature

With hydrogen; triethylamine; nickel; In ethanol;
DOI:10.1021/jm00351a008

Reference yield:

: 6506-86-1
ethyl (6-amino-4-chloro-5-nitropyridin-2-yl)carbamate

: 82585-97-5
ethyl 5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-ylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 45 percent / Et₃N / ethanol / 2.5 h / 75 °C

2: 64 percent / H₂ / Raney nickel / ethanol / 24 h / 760 Torr / Ambient temperature

With hydrogen; triethylamine; nickel; In ethanol;
DOI:10.1021/jm00351a008

Reference yield:

: 82585-44-2
2-{2-(2,4-Dichloro-phenyl)-2-[(E)-hydroxyimino]-ethyl}-isoindole-1,3-dione

: 82585-97-5
ethyl 5-amino-3-(2,4-dichlorophenyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-ylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: hydrazine / ethanol / 22 h / 40 °C

2: 45 percent / Et₃N / ethanol / 2.5 h / 75 °C

3: 64 percent / H₂ / Raney nickel / ethanol / 24 h / 760 Torr / Ambient temperature

With hydrogen; triethylamine; hydrazine; nickel; In ethanol;
DOI:10.1021/jm00351a008