1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)-

Base Information

• Chemical Name: 1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)-
• CAS No.: 849132-72-5
• Molecular Formula: C8H3Cl2FN2OS
• Molecular Weight: 265.095
• DSSTox Substance ID: DTXSID20467338
• NSC Number: 726614
• Wikidata: Q82294264

Synonyms:849132-72-5;5-(2,4-Dichloro-5-fluorophenyl)-1,3,4-oxadiazole-2(3H)-thione;1,4-oxadiazole derivative;1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)-;DTXSID20467338;NSC726614;NSC-726614

Chemical Property of 1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)-

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 263.9327174
• Heavy Atom Count: 15
• Complexity: 315

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1F)Cl)Cl)C2=NNC(=S)O2

Technology Process of 1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)-

There total 4 articles about 1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

carbon disulfide (75-15-0,12122-00-8) + 2,4-Dichloro-5-fluorobenzoic acid hydrazide (328402-46-6) → 5-(2,4-dichloro-5-fluoro-phenyl)-3H-[1,3,4]oxadiazole-2-thione (849132-72-5)

Guidance literature:

With potassium hydroxide; for 2h; Heating;

Reference yield:

2,4-Dichloro-5-fluorobenzoic acid ethyl ester (103318-75-8) → 5-(2,4-dichloro-5-fluoro-phenyl)-[1,3,4]oxadiazole-2-thiol (849132-72-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / methanol / 6 h / Heating

2: KOH / ethanol / 8 h / Heating

With potassium hydroxide; hydrazine hydrate; In methanol; ethanol;

DOI:10.1016/j.bmcl.2006.01.026

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + 2,4-Dichloro-5-fluorobenzoic acid hydrazide (328402-46-6) → 5-(2,4-dichloro-5-fluoro-phenyl)-[1,3,4]oxadiazole-2-thiol (849132-72-5)

Guidance literature:

With potassium hydroxide; In ethanol; for 8h; Heating;

DOI:10.1016/j.bmcl.2006.01.026

upstream raw materials:

carbon disulfide

2,4-Dichloro-5-fluorobenzoic acid hydrazide

2,4-Dichloro-5-fluorobenzoic acid ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 849132-72-5 1,3,4-Oxadiazole-2(3H)-thione, 5-(2,4-dichloro-5-fluorophenyl)-

Send

Send

Metric Ton KG G Pound L ML

Send

Send