Technology Process of Benzeneacetic acid,
(1R,3Z)-1-hexyl-12-oxo-12-(2,2,2-trichloroethoxy)-3-dodecenyl ester
There total 2 articles about Benzeneacetic acid,
(1R,3Z)-1-hexyl-12-oxo-12-(2,2,2-trichloroethoxy)-3-dodecenyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; dicyclohexyl-carbodiimide;
In
toluene;
at 20 ℃;
for 0.5h;
DOI:10.1124/jpet.104.074864
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 100 percent / dicyclohexylcarbodiimide; 4-dimethylaminopyridine / toluene / 18 h / 20 °C
2: 100 percent / dicyclohexylcarbodiimide; 4-dimethylaminopyridine / toluene / 0.5 h / 20 °C
With
dmap; dicyclohexyl-carbodiimide;
In
toluene;
DOI:10.1124/jpet.104.074864
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 53 percent / activated Zn powder / acetic acid; methanol / 20 °C
2: 35 percent / triethylamine hydrochloride; propylphosphonic acid anhydride / CH2Cl2 / 3 h / 20 °C
3: 100 percent / H2 / Pd(C) / 12 h / 20 °C / ballon pressure
With
hydrogen; triethylamine hydrochloride; 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; zinc;
palladium on activated charcoal;
In
methanol; dichloromethane; acetic acid;
DOI:10.1124/jpet.104.074864
