4-Benzyloxy-biphenyl

Base Information

• Chemical Name: 4-Benzyloxy-biphenyl
• CAS No.: 84954-30-3
• Molecular Formula: C19H16O
• Molecular Weight: 260.335
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID20389208
• Nikkaji Number: J1.264.356J
• Wikidata: Q82184751
• Mol file: 84954-30-3.mol

Synonyms:4-Benzyloxy-biphenyl;4-benzyloxybiphenyl;84954-30-3;1-phenyl-4-phenylmethoxybenzene;1,1'-Biphenyl, 4-(phenylmethoxy)-;1-(Benzyloxy)-4-phenylbenzene;4-Benzyloxy-1,1'-biphenyl;SCHEMBL1096817;DTXSID20389208;MFCD00658355;AKOS000746200

Chemical Property of 4-Benzyloxy-biphenyl

Chemical Property:

• Vapor Pressure: 1.15E-06mmHg at 25°C
• Boiling Point: 413.4oC at 760 mmHg
• Flash Point: 167.9oC
• PSA: 9.23000
• Density: 1.087g/cm3
• LogP: 4.93260
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 260.120115130
• Heavy Atom Count: 20
• Complexity: 255

Purity/Quality:

4-Benzyloxybiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC=C(C=C2)C3=CC=CC=C3

Technology Process of 4-Benzyloxy-biphenyl

There total 32 articles about 4-Benzyloxy-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-chlorophenyl benzyl ether (7700-27-8) + C17H22BNO → 4-benzyloxybiphenyl (84954-30-3)

Guidance literature:

With triphenyl phosphite; potassium phosphate tribasic trihydrate; palladium diacetate; 1,3-bis[2,6-diisopropylphenyl]imidazolium chloride; In tert-butyl alcohol; at 80 ℃; for 12h; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.jorganchem.2017.05.013

Reference yield: 98.0%

4-chlorophenyl benzyl ether (7700-27-8) + oxybis(diphenylborane) (4426-21-5) → 4-benzyloxybiphenyl (84954-30-3)

Guidance literature:

With triphenyl phosphite; potassium phosphate tribasic trihydrate; N,N′-bis(2,6-diisopropylphenyl)imidazol-2-ylidene hydrochloride; palladium diacetate; In tert-butyl alcohol; at 80 ℃; for 12h; Reagent/catalyst; Solvent; Temperature; Inert atmosphere;

DOI:10.1021/jo301335x

Reference yield: 97.0%

p-benzyloxyphenylbromide (6793-92-6) + phenylboronic acid (98-80-6) → 4-benzyloxybiphenyl (84954-30-3)

Guidance literature:

With sodium carbonate; In ethanol; water; at 20 ℃; Green chemistry;

DOI:10.1055/s-0033-1338293

upstream raw materials:

4-Phenylphenol

benzyl chloride

benzyl bromide

benzyldimethylphenylammonium chloride

Downstream raw materials:

4-Phenylphenol

benzyl radical

4-phenylbenzhydrol

4-butoxy-1,1’-biphenyl