3-methoxy-N1,N1-dimethylbenzene-1,4-diamine

Base Information

• Chemical Name: 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine
• CAS No.: 7474-82-0
• Molecular Formula: C9H14N2O
• Molecular Weight: 166.223
• Hs Code.: 2922290090
• Mol file: 7474-82-0.mol

Synonyms:2-Methoxy-N4,N4-dimethyl-p-phenylendiamin;3-methoxy-N,N-dimethyl-benzene-1,4-diamine;2-methoxy-N4,N4-dimethyl-p-phenylenediamine;3-methoxy-N1,N1-dimethylbenzene-1,4-diamine;

Chemical Property of 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine

Chemical Property:

• Vapor Pressure: 0.00862mmHg at 25°C
• Boiling Point: 266.5°C at 760 mmHg
• Flash Point: 115°C
• PSA: 38.49000
• Density: 1.081g/cm³
• LogP: 1.92460
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

99% ^*data from raw suppliers

3-Methoxy-1-n,1-n-dimethylbenzene-1,4-diamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine

There total 5 articles about 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

3-methoxy-N,N-dimethyl-4-nitroaniline (14703-82-3) → 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine (7474-82-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethyl acetate; for 0.5h; under 2585.81 Torr;

Reference yield:

C11H16N2O2 (7475-00-5) → 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine (7474-82-0)

Guidance literature:

With sulfuric acid; In methanol; at 60 ℃; for 4h;

DOI:10.1021/ic200032e

Reference yield:

→ 3-methoxy-N1,N1-dimethylbenzene-1,4-diamine (7474-82-0)

Guidance literature:

With tin(ll) chloride;

DOI:10.1021/ja01871a043

upstream raw materials:

C₁₁H₁₆N₂O₂

3-methoxy-N,N-dimethyl-4-nitroaniline

4-fluoro-2-methoxy-1-nitrobenzene

Downstream raw materials:

C₁₅H₂₂N₂O₃

N-(3-(7-(4-(dimethylamino)-2-methoxyphenylamino)-3-methyl-2-oxo-3,4-dihydropyrimido[4,5-d]pyrimidin-1(2H)-yl)phenyl)acrylamide

Refernces

• 1、 Xue, Lin,Li, Guoping,Liu, Qing,Wang, Huanhuan,Liu, Chun,Ding, Xunlei,He, Shenggui,Jiang, Hua. "Ratiometric fluorescent sensor based on inhibition of resonance for detection of cadmium in aqueous solution and living cells". experimental part. p. 3680 - 3690. Retrieved 2011/06/27.
• 2、 -. "PYRIMIDINE INHIBITORS OF KINASE ACTIVITY". Page/Page column 83. . Retrieved 2010/12/26.