N,N-bis(2-chloroethyl)heptan-1-aminium chloride

Base Information

• Chemical Name: N,N-bis(2-chloroethyl)heptan-1-aminium chloride
• CAS No.: 101914-02-7
• Molecular Formula: C₁₁H₂₃Cl₂N*ClH
• Molecular Weight: 276.677
• Mol file: 101914-02-7.mol

Synonyms:1-Heptanamine,N,N-bis(2-chloroethyl)-, hydrochloride (9CI)

Chemical Property of N,N-bis(2-chloroethyl)heptan-1-aminium chloride

Chemical Property:

• Vapor Pressure: 0.0318mmHg at 25°C
• Boiling Point: 243.6°Cat760mmHg
• Flash Point: 101.1°C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-bis(2-chloroethyl)heptan-1-aminium chloride

There total 2 articles about N,N-bis(2-chloroethyl)heptan-1-aminium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

n-heptyldiethanolamine (52891-01-7) → Bis-(2-chloro-ethyl)-heptyl-amine; hydrochloride (101914-02-7)

Guidance literature:

With thionyl chloride; In chloroform; E_. Wilson and M_. Tishler, J_. Am_. Chem_. Soc_., 73, 3635 ⁽¹⁹⁵¹⁾;

Reference yield:

1-Bromoheptane (629-04-9) → Bis-(2-chloro-ethyl)-heptyl-amine; hydrochloride (101914-02-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / ethanol / Heating; E_. Wilson and M_. Tishler, J_. Am_. Chem_. Soc_., 73, 3635 ⁽¹⁹⁵¹⁾

2: thionyl chloride / CHCl₃ / E_. Wilson and M_. Tishler, J_. Am_. Chem_. Soc_., 73, 3635 ⁽¹⁹⁵¹⁾

With thionyl chloride; In ethanol; chloroform;

Reference yield:

4-pentyloxyaniline (39905-50-5) + Bis-(2-chloro-ethyl)-heptyl-amine; hydrochloride (101914-02-7) → N-n-Heptyl-N'-(4-pentyloxyphenyl)-piperazine (129992-48-9)

Guidance literature:

With sodium carbonate; Yield given. Multistep reaction; 1.) methanol, reflux, 6 h, 2.) reflux, 2-4 h;

upstream raw materials:

n-heptyldiethanolamine

1-Bromoheptane

Downstream raw materials:

N-n-Heptyl-N'-(4-pentyloxyphenyl)-piperazine

Refernces