Carbamic acid, ethyl[[5-[4-fluoro-3-[[4-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imid azol-2-yl]carbonyl]phenyl]-4-methyl-3-pyridinyl]methyl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, ethyl[[5-[4-fluoro-3-[[4-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imid azol-2-yl]carbonyl]phenyl]-4-methyl-3-pyridinyl]methyl]-, 1,1-dimethylethyl ester
CAS No.:850892-93-2
Molecular Formula:C31H43FN4O4Si
Molecular Weight:582.791
Hs Code.:

Carbamic acid,
ethyl[[5-[4-fluoro-3-[[4-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imid
azol-2-yl]carbonyl]phenyl]-4-methyl-3-pyridinyl]methyl]-, 1,1-dimethylethyl
ester

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Chemical Property of Carbamic acid, ethyl[[5-[4-fluoro-3-[[4-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imid azol-2-yl]carbonyl]phenyl]-4-methyl-3-pyridinyl]methyl]-, 1,1-dimethylethyl ester

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Technology Process of Carbamic acid, ethyl[[5-[4-fluoro-3-[[4-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imid azol-2-yl]carbonyl]phenyl]-4-methyl-3-pyridinyl]methyl]-, 1,1-dimethylethyl ester

There total 1 articles about Carbamic acid, ethyl[[5-[4-fluoro-3-[[4-methyl-1-[[2-(trimethylsilyl)ethoxy]methyl]-1H-imid azol-2-yl]carbonyl]phenyl]-4-methyl-3-pyridinyl]methyl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: 351458-27-0
(5-Bromo-4-methyl-pyridin-3-ylmethyl)-ethyl-carbamic acid tert-butyl ester

: 850892-92-1
(2-fluoro-5-iodophenyl)(4-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)methanone

: 850892-93-2
tert-Butyl ethyl[(5-{4-fluoro-3-[(4-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)carbonyl]phenyl}-4-methylpyridin-3-yl)methyl]carbamate

Guidance literature:: (2-fluoro-5-iodophenyl)(4-methyl-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)methanone; With potassium acetate; bis(pinacol)diborane; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In ISOPROPYLAMIDE; at 80 - 90 ℃; for 3h;

(5-Bromo-4-methyl-pyridin-3-ylmethyl)-ethyl-carbamic acid tert-butyl ester; With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ISOPROPYLAMIDE; water; at 90 - 100 ℃; for 24h;