Morphinan-8-one,6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5a)- (9CI)

Base Information

Chemical Name:Morphinan-8-one,6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5a)- (9CI)
CAS No.:94713-16-3
Molecular Formula:C18H19 N O3
Molecular Weight:297.354
Hs Code.:

Synonyms:Pseudocodeinone(7CI)

Suppliers and Price of Morphinan-8-one,6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5a)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of Morphinan-8-one,6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5a)- (9CI)

Chemical Property:

Boiling Point:436.3°Cat760mmHg
Flash Point:217.7°C
PSA：38.77000
Density:1.34g/cm³
LogP:1.64720

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Morphinan-8-one,6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5a)- (9CI)

There total 15 articles about Morphinan-8-one,6,7-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5a)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 509-55-7
Pseudocodein

: 94713-16-3
4,5-epoxy-3-methoxy-17-methyl-morphin-6-en-8-one

Guidance literature:: With chromium(III) oxide; sulfuric acid;

Reference yield:

: 466-96-6
pseudocodeine

: 94713-16-3
4,5-epoxy-3-methoxy-17-methyl-morphin-6-en-8-one

Guidance literature:: With chromium(III) oxide; sulfuric acid;

Reference yield:

: 508-54-3
14-hydroxycodeinone

: 94713-16-3
4,5α-epoxy-3-methoxy-17-methyl-(14ξ)-morphin-6-en-8-one

Guidance literature:: Multi-step reaction with 9 steps

1: NaBH₄ / dioxane

2: pyridine

3: aq. acetic acid / Heating

5: methanol / Heating

6: (i) aq. AcOH, (ii) /BRN= 385737/

7: aq. KOH / ethanol

8: MnO₂ / CHCl₃

9: H₂, aq. HCl / PtO₂ / acetic acid

With hydrogenchloride; manganese(IV) oxide; potassium hydroxide; sodium tetrahydroborate; hydrogen; platinum(IV) oxide; In 1,4-dioxane; pyridine; methanol; ethanol; chloroform; acetic acid;
DOI:10.1039/jr9600000773