Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]-

Base Information

Chemical Name:Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]-
CAS No.:852619-88-6
Molecular Formula:C18H24N2Si
Molecular Weight:296.487
Hs Code.:
DSSTox Substance ID:DTXSID90469965
Nikkaji Number:J2.245.600H
Wikidata:Q82297911

Synonyms:Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]-;852619-88-6;SCHEMBL12909643;DTXSID90469965

Suppliers and Price of Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]-

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:296.170875308
Heavy Atom Count:21
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCC1C2=C(C=CN=C2)[Si](C)(C)C3=CC=CC=C3
Isomeric SMILES:CN1CCC[C@H]1C2=C(C=CN=C2)[Si](C)(C)C3=CC=CC=C3

Technology Process of Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]-

There total 2 articles about Pyridine, 4-(dimethylphenylsilyl)-3-[(2S)-1-methyl-2-pyrrolidinyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 852619-86-4
1-[(4R)-4-(dimethylphenylsilanyl)-3-((2S)-1-methyl-pyrrolidin-2-yl)-4H-pyridin-1-yl]-2,2-dimethyl-propan-1-one

: 852619-88-6
4-(dimethylphenylsilanyl)-3-((2S)-1-methylpyrrolidin-2-yl)pyridine

Guidance literature:: With sulfur; In toluene; at 90 ℃; for 48h;

Reference yield:

: 1-[4-(dimethylphenylsilanyl)-3-((2S)-1-methyl-pyrrolidin-2-yl)-4H-pyridin-1-yl]-2,2-dimethyl-propan-1-one

: 852619-88-6
4-(dimethylphenylsilanyl)-3-((2S)-1-methylpyrrolidin-2-yl)pyridine

Guidance literature:: With pyrographite; sulfur; In toluene; at 90 ℃; for 24h;
DOI:10.1021/ol0520469

Reference yield: 43.0%

: 852619-88-6
4-(dimethylphenylsilanyl)-3-((2S)-1-methylpyrrolidin-2-yl)pyridine

: (S)-2-chloro-4-(dimethylphenylsilanyl)-5-(1-methylpyrrolidin-2-yl)pyridine

Guidance literature:: 4-(dimethylphenylsilanyl)-3-((2S)-1-methylpyrrolidin-2-yl)pyridine; With n-butyllithium; 2-(N,N-dimethylamino)ethanol; In hexane; at -20 ℃; for 1h;

With hexachloroethane; In hexane; at -78 ℃; for 1h;
DOI:10.1021/ol052196j