1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline

Base Information

Chemical Name:1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline
CAS No.:6043-48-7
Molecular Formula:C₂₇H₄₆O₂
Molecular Weight:402.661
Hs Code.:
DSSTox Substance ID:DTXSID70391654

Synonyms:1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline;345637-80-1;6043-48-7;1-(4-chloro-2,5-dimethylphenyl)sulfonylpyrrolidine-2-carboxylic acid;1-(4-chloro-2,5-dimethylphenylsulfonyl)-2-pyrrolidinecarboxylic acid;CBMicro_041760;Cambridge id 6043487;Oprea1_805588;DTXSID70391654;AKOS000124930;AKOS016879500;BIM-0041832.P001;SR-01000596977;SR-01000596977-1;Z56853700;T0510-5933

Suppliers and Price of 1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline

Chemical Property:

Vapor Pressure:2.73E-11mmHg at 25°C
Boiling Point:511.6°Cat760mmHg
Flash Point:263.2°C
Density:1.42g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:317.0488569
Heavy Atom Count:20
Complexity:475

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1Cl)C)S(=O)(=O)N2CCCC2C(=O)O

Technology Process of 1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline

There total 14 articles about 1-[(4-Chloro-2,5-dimethylphenyl)sulfonyl]proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5847-18-7,51261-49-5,53286-28-5,107740-36-3,5847-17-6
(E)-3β-acetoxy-5,10-seco-cholest-1(10)-en-5-one

: 6043-48-7
5(10->1βH)abeo-5α-Cholest-10(19)-en-3β,5-diol

Guidance literature:: Multi-step reaction with 2 steps

1: H⁺

2: KOH / methanol

With potassium hydroxide; hydrogen cation; In methanol;
DOI:10.1016/S0040-4020(01)97849-4

Reference yield:

: 5847-18-7,51261-49-5,53286-28-5,107740-36-3,5847-17-6
(E)-3β-acetoxy-5,10-seco-cholest-1(10)-en-5-one

: 6043-48-7
5(10->1βH)abeo-5α-Cholest-10(19)-en-3α,5-diol

Guidance literature:: Multi-step reaction with 4 steps

1: H⁺

2: KOH / methanol

3: CrO₃, aq. H₂SO₄ / acetone

4: LiAlH₄ / diethyl ether

With chromium(VI) oxide; potassium hydroxide; lithium aluminium tetrahydride; sulfuric acid; hydrogen cation; In methanol; diethyl ether; acetone;
DOI:10.1016/S0040-4020(01)97849-4