Piperazine, 1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl-

Base Information

Chemical Name:Piperazine, 1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl-
CAS No.:853296-96-5
Molecular Formula:C13H16F3N3O
Molecular Weight:287.285
Hs Code.:

Synonyms:(3-amino-5-trifluoromethyl-phenyl)-(4-methylpiperazin-1-yl)-methanone;3-[(4-methylpiperazin-1-yl)carbonyl]-5-(trifluoromethyl)aniline;Piperazine,1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl;

Suppliers and Price of Piperazine, 1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Piperazine, 1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl-

Chemical Property:

PSA：49.57000
LogP:2.13220

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Piperazine, 1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl-

There total 2 articles about Piperazine, 1-[3-amino-5-(trifluoromethyl)benzoyl]-4-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 853296-95-4
(4-methylpiperazin-1-yl)(3-nitro-5-(trifluoromethyl)phenyl)methanone

: 853296-96-5
3-[(4-methylpiperazin-1-yl)carbonyl]-5-(trifluoro-methyl)aniline

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 3h; under 760.051 Torr;

Reference yield: 75.0%

: 853296-96-5
3-[(4-methylpiperazin-1-yl)carbonyl]-5-(trifluoro-methyl)aniline

Guidance literature:

Reference yield: 50.0%

: 853296-96-5
3-[(4-methylpiperazin-1-yl)carbonyl]-5-(trifluoro-methyl)aniline

: 853296-94-3
3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoro-methyl)aniline

Guidance literature:: 3-[(4-methylpiperazin-1-yl)carbonyl]-5-(trifluoro-methyl)aniline; With dimethylsulfide borane complex; In tetrahydrofuran; at 0 ℃; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃;

With sodium hydroxide; In tetrahydrofuran; water; at 0 ℃;
DOI:10.1016/j.bmc.2010.08.042