1H-Pyrrole, 1-(4-methylphenyl)-2,5-diphenyl-

Base Information

• Chemical Name: 1H-Pyrrole, 1-(4-methylphenyl)-2,5-diphenyl-
• CAS No.: 853-36-1
• Molecular Formula: C23H19N
• Molecular Weight: 309.411
• Mol file: 853-36-1.mol

Synonyms:N-p-Tolyl-2.5-diphenyl-pyrrol;2,5-diphenyl-1-p-tolyl-pyrrole;2,5-diphenyl-1-(p-tolyl)-1H-pyrrole;2,5-Diphenyl-1-p-tolyl-1H-pyrrole;2,5-Diphenyl-1-p-tolyl-pyrrol;2,5-diphenyl-1-p-tolylpyrrole;

Chemical Property of 1H-Pyrrole, 1-(4-methylphenyl)-2,5-diphenyl-

Chemical Property:

• PSA: 4.93000
• LogP: 6.11970

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1H-Pyrrole, 1-(4-methylphenyl)-2,5-diphenyl-

There total 16 articles about 1H-Pyrrole, 1-(4-methylphenyl)-2,5-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

4-methyl-N,N-bis(1-phenylvinyl) aniline (1240239-16-0) → 1-(4-methylphenyl)-2,5-diphenylpyrrole (853-36-1)

Guidance literature:

With iodobenzene; palladium diacetate; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 140 ℃; for 20h; Sealed vial;

DOI:10.1021/jo101674t

Reference yield: 93.0%

1,4-diphenyl-1,3-butadiyne (886-66-8) + p-toluidine (106-49-0,12221-03-3) → 1-(4-methylphenyl)-2,5-diphenylpyrrole (853-36-1)

Guidance literature:

With copper(l) chloride; at 100 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tetlet.2010.06.092

Reference yield: 78.0%

N-(4-methylphenyl)-α-2-propenylbenzenemethanamine (254992-96-6) + phenylboronic acid (98-80-6) → 1-(4-methylphenyl)-2,5-diphenylpyrrole (853-36-1)

Guidance literature:

With copper diacetate; triethylamine; palladium dichloride; In acetonitrile; at 80 ℃; for 12h;

DOI:10.1021/jo502414w

upstream raw materials:

2,4,6-triphenyl-1-(p-tolyl)-1,4-dihydropyrazine

2,6-diphenyl-1,4-bis(p-tolyl)-1,4-dihydropyrazine

4-(4-trifluoromethylphenyl)-2,6-diphenyl-1-(p-tolyl)-1,4-dihydropyrazine

N-phenacyl-p-toluidine

Downstream raw materials:

3-nitro-2,5-diphenyl-1-(p-tolyl)-1H-pyrrole