1H-Indazole-1-carboxylic acid, 3-[5-(2-chloroethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-5-( phenylmethoxy)-, 1,1-dimethylethyl ester

Base Information

Chemical Name:1H-Indazole-1-carboxylic acid, 3-[5-(2-chloroethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-5-( phenylmethoxy)-, 1,1-dimethylethyl ester
CAS No.:854636-90-1
Molecular Formula:C34H36ClN3O6
Molecular Weight:618.129
Hs Code.:

1H-Indazole-1-carboxylic acid,
3-[5-(2-chloroethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-5-(
phenylmethoxy)-, 1,1-dimethylethyl ester

Synonyms:

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Chemical Property of 1H-Indazole-1-carboxylic acid, 3-[5-(2-chloroethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-5-( phenylmethoxy)-, 1,1-dimethylethyl ester

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Technology Process of 1H-Indazole-1-carboxylic acid, 3-[5-(2-chloroethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-5-( phenylmethoxy)-, 1,1-dimethylethyl ester

There total 1 articles about 1H-Indazole-1-carboxylic acid, 3-[5-(2-chloroethoxy)-1-[(1,1-dimethylethoxy)carbonyl]-1H-indol-2-yl]-5-( phenylmethoxy)-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 854636-66-1
5-benzyloxy-3-(1-tert-butoxycarbonyl-5-hydroxy-1H-indol-2-yl)indazole-1-carboxylic acid tert-butyl ester

: 107-04-0
1-Bromo-2-chloroethane

: 854636-90-1
5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-chloro-ethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester

Guidance literature:: With sodium hydroxide; tetrabutylammomium bromide; In dichloromethane; water; at 20 ℃; for 6h;

Reference yield:

: 854636-90-1
5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-chloro-ethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester

: 75-04-7,85404-22-4
ethylamine

: 854637-24-4
5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-diethylaminoethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester

Guidance literature:: With potassium carbonate; potassium iodide; In acetonitrile; at 80 ℃; for 18h;

Reference yield:

: 854636-90-1
5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-chloro-ethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester

: 24424-99-5
di-tert-butyl dicarbonate

: 57260-71-6
1-t-Butoxycarbonylpiperazine

: 854636-97-8
5-Benzyloxy-3-{1-tert-butoxycarbonyl-5-[2-(4-tert-butoxycarbonyl-piperazin-1-yl)ethoxy]-1H-indol-2-yl}indazole-1-carboxylic acid tert-butyl ester

Guidance literature:: 5-benzyloxy-3-[1-tert-butoxycarbonyl-5-(2-chloro-ethoxy)-1H-indol-2-yl]indazole-1-carboxylic acid tert-butyl ester; 1-t-Butoxycarbonylpiperazine; With potassium carbonate; potassium iodide; In acetonitrile; at 85 ℃; for 48h;

di-tert-butyl dicarbonate; With dmap; In dichloromethane; at 20 ℃; for 3h;