2-(Diphenylphosphoryl)butanal

Base Information

• Chemical Name: 2-(Diphenylphosphoryl)butanal
• CAS No.: 85464-09-1
• Molecular Formula: C16H17O2P
• Molecular Weight: 272.284
• DSSTox Substance ID: DTXSID30515571
• Mol file: 85464-09-1.mol

Synonyms:2-(diphenylphosphoryl)butanal;85464-09-1;2-diphenyl-phosphoryl-butyraldehyde;DTXSID30515571

Chemical Property of 2-(Diphenylphosphoryl)butanal

Chemical Property:

• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 272.09661678
• Heavy Atom Count: 19
• Complexity: 306

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C=O)P(=O)(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of 2-(Diphenylphosphoryl)butanal

There total 2 articles about 2-(Diphenylphosphoryl)butanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Diphenylphosphine oxide (4559-70-0) → 2-(Diphenyl-phosphinoyl)-butyraldehyde (85464-09-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / tetrahydrofuran / 2 h / Ambient temperature

In tetrahydrofuran;

DOI:10.1055/s-1982-30050

Reference yield:

C16H18NO3P (85464-07-9) → 2-(Diphenyl-phosphinoyl)-butyraldehyde (85464-09-1)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1055/s-1982-30050

Reference yield: 89.0%

2-(Diphenyl-phosphinoyl)-butyraldehyde (85464-09-1) → <1-(hydroxymethyl)propyl>diphenylphosphine oxide (89841-29-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; for 16h; Heating;

DOI:10.1246/bcsj.56.3533

upstream raw materials:

C₁₆H₁₈NO₃P

Diphenylphosphine oxide

Downstream raw materials:

<1-(hydroxymethyl)propyl>diphenylphosphine oxide