Naphthalen-2-yl 2-benzamido-3-phenylpropanoate

Base Information

• Chemical Name: Naphthalen-2-yl 2-benzamido-3-phenylpropanoate
• CAS No.: 2134-24-9
• Molecular Formula: C26H21NO3
• Molecular Weight: 395.458
• Hs Code.: 2924299090
• European Community (EC) Number: 218-364-6
• DSSTox Substance ID: DTXSID30943895
• Mol file: 2134-24-9.mol

Synonyms:2134-24-9;15873-25-3;N-Benzoyl-DL-phenylalanine 2-Naphthyl Ester;naphthalen-2-yl 2-benzamido-3-phenylpropanoate;N-BENZOYL-DL-PHENYLALANINE 2-NAPHTHYL ESTER [FOR DETERMINATION OF CHYMOTRYPSIN];2-naphthyl n-benzoylphenylalaninate;naphthalen-2-yl 3-phenyl-2-(phenylformamido)propanoate;Bz-DL-Phe-beta-naphthyl ester;SCHEMBL4953990;DTXSID30943895;EINECS 218-364-6;MFCD00021607;AKOS003349233;HY-W141794;SB83667;AS-46864;N-benzoyl-dl-phenylalanine-2-naphthylester;2-Naphthyl N-benzoyl-3-phenyl-DL-alaninate;B0309;Benzoyl-DL-phenylalanine beta-naphthyl ester;CS-0201591;FT-0634056;naphthalen-2-yl2-benzamido-3-phenylpropanoate;Phenylalanine,N-benzoyl-,2-naphthalenyl ester;2-naphthyl 2-(benzoylamino)-3-phenylpropanoate;N-Benzoyl-DL-phenylalanine beta-naphthyl ester;N-BenZoyl-DL-phenylalanine 2-Naphtyl ester (BZ-DL-Phe-beta-naphthyl ester);N-{1-[(Naphthalen-2-yl)oxy]-1-oxo-3-phenylpropan-2-yl}benzenecarboximidic acid

Chemical Property of Naphthalen-2-yl 2-benzamido-3-phenylpropanoate

Chemical Property:

• Vapor Pressure: 4.1E-17mmHg at 25°C
• Melting Point: 156-157 °C
• Refractive Index: 1.648
• Boiling Point: 656.6 °C at 760 mmHg
• PKA: 12.96±0.46(Predicted)
• Flash Point: 350.9 °C
• PSA: 55.40000
• Density: 1.222 g/cm³
• LogP: 5.17740
• Storage Temp.: −20°C
• XLogP3: 5.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 395.15214353
• Heavy Atom Count: 30
• Complexity: 565

Purity/Quality:

97% ^*data from raw suppliers

N-BENZOYL-DL-PHENYLALANINE-2-NAPHTHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(C(=O)OC2=CC3=CC=CC=C3C=C2)NC(=O)C4=CC=CC=C4

Technology Process of Naphthalen-2-yl 2-benzamido-3-phenylpropanoate

There total 2 articles about Naphthalen-2-yl 2-benzamido-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-N-benzoylphenylalanine (2566-22-5,2901-76-0,37002-52-1) + trifluoroacetic anhydride (407-25-0) → N-benzoyl-DL-phenylalanine β-naphthyl ester (2134-24-9)

Guidance literature:

anschliessendes Erhitzen mit <2>Naphthol;

Reference yield:

→ N-benzoyl-DL-phenylalanine β-naphthyl ester (2134-24-9)

Guidance literature:

Aus 4-Benzyl-2-phenyl-Δ²-oxazolin-5-on, <2>Naphthol (110-115grad);

Reference yield:

N-benzoyl-DL-phenylalanine β-naphthyl ester (2134-24-9) → N-benzoyl-L-phenylalanine β-naphthyl ester (15873-25-3) + N-benzoyl-D-phenylalanine β-naphthyl ester (211681-82-2)

Guidance literature:

With N-[(S)-1-phenylethyl]carbamoyl-derivatized cyclofructan-6 column; In ethanol; n-heptane; trifluoroacetic acid; at 20 ℃; Resolution of racemate;

DOI:10.1021/ac902257a

upstream raw materials:

DL-N-benzoylphenylalanine

trifluoroacetic anhydride

Downstream raw materials:

N-benzoyl-L-phenylalanine β-naphthyl ester

N-benzoyl-D-phenylalanine β-naphthyl ester