1-(4-Chlorobenzyl)-1h-indole

Base Information

Chemical Name:1-(4-Chlorobenzyl)-1h-indole
CAS No.:85607-00-7
Molecular Formula:C15H12ClN
Molecular Weight:241.72
Hs Code.:
DSSTox Substance ID:DTXSID10359516
Nikkaji Number:J1.632.420E
Wikidata:Q82140755

Synonyms:1-(4-chlorobenzyl)-1h-indole;85607-00-7;1-[(4-chlorophenyl)methyl]indole;N-(4-chlorobenzyl)indole;1-(4-chlorobenzyl)indole;SCHEMBL2247137;DTXSID10359516;XWHLRMOIAGSFJN-UHFFFAOYSA-N;AKOS008968041

Suppliers and Price of 1-(4-Chlorobenzyl)-1h-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 14 raw suppliers

Chemical Property of 1-(4-Chlorobenzyl)-1h-indole

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:241.0658271
Heavy Atom Count:17
Complexity:247

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CN2CC3=CC=C(C=C3)Cl

Technology Process of 1-(4-Chlorobenzyl)-1h-indole

There total 8 articles about 1-(4-Chlorobenzyl)-1h-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 120-72-9
indole

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 85607-00-7
1-(4'-chlorobenzyl)-indole

Guidance literature:: indole; With 80percent NaH; In N,N-dimethyl-formamide; at 70 ℃;

1-Chloro-4-(chloromethyl)benzene; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Further stages.;
DOI:10.1002/1099-0690(200110)2001:20<3843::AID-EJOC3843>3.0.CO;2-P

Reference yield: 94.0%

: 496-15-1
1-indoline

: 873-76-7
para-Chlorobenzyl alcohol

: 85607-00-7
1-(4'-chlorobenzyl)-indole

Guidance literature:: With cesiumhydroxide monohydrate; C₃₀H₂₉BrMnNO₂P₂; In 2,2,2-trifluoroethanol; toluene; at 135 ℃; for 36h; regioselective reaction; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.0c01270

Reference yield: 85.0%

: 120-72-9
indole

: 622-95-7
4-chlorobenzyl bromide

: 85607-00-7
1-(4'-chlorobenzyl)-indole

Guidance literature:: indole; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

4-chlorobenzyl bromide; In dimethyl sulfoxide; at 20 ℃; for 16h;
DOI:10.1039/c8ob01146j