4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one

Base Information

Chemical Name:4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one
CAS No.:85808-02-2
Molecular Formula:C16H20O3
Molecular Weight:260.333
Hs Code.:
DSSTox Substance ID:DTXSID40528551

Synonyms:85808-02-2;DTXSID40528551;4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one

Suppliers and Price of 4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one

Chemical Property:

XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:260.14124450
Heavy Atom Count:19
Complexity:316

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C=C(C(CC1=O)CO)CCOCC2=CC=CC=C2

Technology Process of 4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one

There total 3 articles about 4-[2-(Benzyloxy)ethyl]-5-(hydroxymethyl)cyclohex-3-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85807-96-1
[8-Benzenesulfonyl-8-(2-benzyloxy-ethyl)-1,4-dioxa-spiro[4.5]dec-9-en-7-ylmethoxy]-tert-butyl-dimethyl-silane

: 85808-02-2
5-(hydroxymethyl)-4-<2-(benzyloxy)ethyl>-3-cyclohexenone

Guidance literature:: With sodium amalgam; pyridinium p-toluenesulfonate; Yield given. Multistep reaction; 1.) Na₂HPO₄-buffered methanol, 2.) aq. acetone;
DOI:10.1016/S0040-4039(00)85776-7

Reference yield:

: 1462-37-9
bromoethyl-2-benzyl ether

: 85808-02-2
5-(hydroxymethyl)-4-<2-(benzyloxy)ethyl>-3-cyclohexenone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 2.) 18.5 h

2: 1.) NaHPO₄, Na(Hg), 2.) PPTS / 1.) methanol, 4 h, 2.) wet acetone, reflux, 22 h

With sodium amalgam; camphor-10-sulfonic acid; pyridinium p-toluenesulfonate; sodium hydride;
DOI:10.1021/jo00173a040

Reference yield:

: 87640-87-7
(8-Benzenesulfonyl-1,4-dioxa-spiro[4.5]dec-9-en-7-ylmethoxy)-tert-butyl-dimethyl-silane

: 85808-02-2
5-(hydroxymethyl)-4-<2-(benzyloxy)ethyl>-3-cyclohexenone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 2.) 18.5 h

2: 1.) NaHPO₄, Na(Hg), 2.) PPTS / 1.) methanol, 4 h, 2.) wet acetone, reflux, 22 h

With sodium amalgam; camphor-10-sulfonic acid; pyridinium p-toluenesulfonate; sodium hydride;
DOI:10.1021/jo00173a040