5-Hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxyflavone

Base Information

• Chemical Name: 5-Hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxyflavone
• CAS No.: 485-53-0
• Molecular Formula: C19H16O8
• Molecular Weight: 372.33
• Mol file: 485-53-0.mol

Synonyms:5-hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxyflavone;5-Hydroxy-3,6,7-trimethoxy-3',4'-methylendioxy-flavon;2-benzo[1,3]dioxol-5-yl-5-hydroxy-3,6,7-trimethoxy-chromen-4-one;Melisimplin;Milisimplin;2-Benzo[1,3]dioxol-5-yl-5-hydroxy-3,6,7-trimethoxy-chromen-4-on;5-hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxy-flavone;

Chemical Property of 5-Hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxyflavone

Chemical Property:

• PSA: 96.59000
• LogP: 2.92010

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxyflavone

There total 9 articles about 5-Hydroxy-3,6,7-trimethoxy-3',4'-methylenedioxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzo[d][1,3]dioxole-5-carboxylic anhydride (6938-53-0) → melisimplin (485-53-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium-salt of/the/ piperonylic acid / 175 °C / 300 Torr

2: acetone; potassium carbonate

3: aluminium chloride; diethyl ether

With aluminium trichloride; diethyl ether; 3,4-methylenedioxybenzoic acid potassium salt; potassium carbonate; acetone;

DOI:10.1039/jr9500002376

Reference yield:

melisimplexin (479-77-6) → melisimplin (485-53-0)

Guidance literature:

With aluminium trichloride; diethyl ether;

DOI:10.1039/jr9500002376

Reference yield:

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone (14639-73-7) → melisimplin (485-53-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium-salt of/the/ piperonylic acid / 175 °C / 300 Torr

2: acetone; potassium carbonate

3: aluminium chloride; diethyl ether

With aluminium trichloride; diethyl ether; 3,4-methylenedioxybenzoic acid potassium salt; potassium carbonate; acetone;

DOI:10.1039/jr9500002376

upstream raw materials:

melisimplexin

2-benzo[1,3]dioxol-5-yl-5,6-dihydroxy-3,7-dimethoxy-chromen-4-one

dimethyl sulfate

1-(3,6-dihydroxy-2,4-dimethoxy-phenyl)-2-methoxy-ethanone