4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol

Base Information

Chemical Name:4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol
CAS No.:113628-69-6
Molecular Formula:C₂₁H₂₃N₅O₃
Molecular Weight:393.445
Hs Code.:
DSSTox Substance ID:DTXSID30921138
Wikidata:Q82893895
ChEMBL ID:CHEMBL14645

Synonyms:BRN 6445482;4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol;Phenol, 4-(6-(bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)-;113628-69-6;CHEMBL14645;DTXSID30921138;C21H23N5O3;C21-H23-N5-O3;LS-104078;4-{6-[Bis(2-methoxyethyl)amino][1,2,4]triazolo[3,4-a]phthalazin-3(2H)-ylidene}cyclohexa-2,5-dien-1-one

Suppliers and Price of 4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol

Chemical Property:

Vapor Pressure:8.15E-11mmHg at 25°C
Boiling Point:517.5°Cat760mmHg
Flash Point:266.8°C
Density:1.3g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:393.18008961
Heavy Atom Count:29
Complexity:497

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCCN(CCOC)C1=NN2C(=NN=C2C3=CC=CC=C31)C4=CC=C(C=C4)O

Technology Process of 4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol

There total 4 articles about 4-(6-(Bis(2-methoxyethyl)amino)-1,2,4-triazolo(3,4-a)phthalazin-3-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 111-95-5
Bis-(2-methoxyethyl)amine

: 113628-63-0
4-(6-Chloro-[1,2,4]triazolo[3,4-a]phthalazin-3-yl)-phenol

: 113628-69-6
4-{6-[Bis-(2-methoxy-ethyl)-amino]-[1,2,4]triazolo[3,4-a]phthalazin-3-yl}-phenol

Guidance literature:: at 140 ℃; for 30h;
DOI:10.1021/jm00401a010

Reference yield:

: 27914-73-4
4-acetoxybenzoyl chloride

: 113628-69-6
4-{6-[Bis-(2-methoxy-ethyl)-amino]-[1,2,4]triazolo[3,4-a]phthalazin-3-yl}-phenol

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / Et₃N / dioxane / 5 h / Heating

2: 80 percent / OH^-

3: 70 percent / 30 h / 140 °C

With hydroxide; triethylamine; In 1,4-dioxane;
DOI:10.1021/jm00401a010

Reference yield:

: 51935-42-3,59275-72-8
1-chloro-4-hydrazinophthalazine

: 113628-69-6
4-{6-[Bis-(2-methoxy-ethyl)-amino]-[1,2,4]triazolo[3,4-a]phthalazin-3-yl}-phenol

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / Et₃N / dioxane / 5 h / Heating

2: 80 percent / OH^-

3: 70 percent / 30 h / 140 °C

With hydroxide; triethylamine; In 1,4-dioxane;
DOI:10.1021/jm00401a010