5,7-Dodecadiyne-1,12-diol

Base Information

• Chemical Name: 5,7-Dodecadiyne-1,12-diol
• CAS No.: 74602-32-7
• Molecular Formula: C12H18 O2
• Molecular Weight: 194.27
• Mol file: 74602-32-7.mol

Synonyms:5,7-Dodecadiyn-1,12-diol

Chemical Property of 5,7-Dodecadiyne-1,12-diol

Chemical Property:

• Vapor Pressure: 4.81E-07mmHg at 25°C
• Melting Point: 49.5 °C
• Boiling Point: 371.8°C at 760 mmHg
• PKA: 14.72±0.10(Predicted)
• Flash Point: 178.6°C
• PSA: 40.46000
• Density: 1.032g/cm³
• LogP: 1.31840

Purity/Quality:

99% ^*data from raw suppliers

5,7-DODECADIYN-1,12-DIOL ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,7-Dodecadiyne-1,12-diol

There total 2 articles about 5,7-Dodecadiyne-1,12-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

5-hexyl-1-ol (928-90-5) + 1,4-diiodo-2,3,5,6-tetrafluorobenzene (392-57-4) → 5,7-dodecadiyne-1,12-diol (74602-32-7) + 1,4-bis(6'-hydroxyhex-1'-ynyl)-2,3,5,6-tetrafluorobenzene

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; at 90 ℃; for 24h; Inert atmosphere; Darkness;

DOI:10.1002/cmdc.201800331

Reference yield: 40.0%

5-hexyl-1-ol (928-90-5) + 1,2-Diiodobenzene (615-42-9) → 5,7-dodecadiyne-1,12-diol (74602-32-7) + 1,2-bis(6'-hydroxyhex-1'-ynyl)benzene

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In dichloromethane; at 50 ℃; for 21h; Inert atmosphere; Darkness;

DOI:10.1002/cmdc.201800331

Reference yield: 91.0%

5,7-dodecadiyne-1,12-diol (74602-32-7) → dodeca-5,7-diynedioic acid (28393-04-6)

Guidance literature:

With Jones reagent; In acetone; at 0 ℃;

DOI:10.1246/bcsj.20160347

upstream raw materials:

5-hexyl-1-ol

1,2-Diiodobenzene

1,4-diiodo-2,3,5,6-tetrafluorobenzene

Downstream raw materials:

5,7-dodecacadiyn-1,12-ylene di(1,2-diphenylcycloprpene-3-carboxylate)

5,7-decadiyne-1,12-diyl bis[N-(3,4,5-trimethoxyphenyl)carbamate]

5,7-decadiyne-1,12-diyl bis[N-(3,4,5-tridodecyloxyphenyl)carbamate]

dodeca-5,7-diynedioic acid

Refernces