tert-Butyl (3-fluoro-4-hydroxyphenyl)carbamate

Base Information

Chemical Name:tert-Butyl (3-fluoro-4-hydroxyphenyl)carbamate
CAS No.:859537-27-2
Molecular Formula:C11H14FNO3
Molecular Weight:227.235
Hs Code.:
Mol file:859537-27-2.mol

Synonyms:tert-Butyl (3-Fluoro-4-hydroxyphenyl)carbamate;(3-Fluoro-4-hydroxyphenyl)carbamic acid tert-butyl ester;2-Fluoro-4-(tert-butoxycarbonylamino)phenol;4-(tert-Butoxycarbonylamino)-2-fluorophenol;Carbamic acid, (3-fluoro-4-hydroxyphenyl)-, 1,1-dimethylethyl ester;

Suppliers and Price of tert-Butyl (3-fluoro-4-hydroxyphenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of tert-Butyl (3-fluoro-4-hydroxyphenyl)carbamate

Chemical Property:

Vapor Pressure:0.004mmHg at 25°C
PSA：58.56000
LogP:2.95130

Purity/Quality:: 98%Min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl (3-fluoro-4-hydroxyphenyl)carbamate

There total 3 articles about tert-Butyl (3-fluoro-4-hydroxyphenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 859537-27-2
N-(3-fluoro-4-hydroxyphenyl)carbamic acid tert-butyl ester

Guidance literature:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 403-19-0
2-fluoro-4-nitrophenol

: 859537-27-2
N-(3-fluoro-4-hydroxyphenyl)carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; for 11h;

Reference yield:

: 403-19-0
2-fluoro-4-nitrophenol

: 859537-27-2
N-(3-fluoro-4-hydroxyphenyl)carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd-C

2: 56 percent / Et₃N / tetrahydrofuran

With hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1016/j.bmc.2006.06.019