(2R)-2-(3-bromophenyl)-1,2-propanediol

Base Information

Chemical Name:(2R)-2-(3-bromophenyl)-1,2-propanediol
CAS No.:861664-75-7
Molecular Formula:C9H11BrO2
Molecular Weight:231.089
Hs Code.:
DSSTox Substance ID:DTXSID20435698
Nikkaji Number:J680.476D
Wikidata:Q82250774

Synonyms:(2R)-2-(3-bromophenyl)-1,2-propanediol;861664-75-7;SCHEMBL3556113;DTXSID20435698;MBDDWKQRVLFVOT-VIFPVBQESA-N;(R)-2-(3-Bromophenyl)-1,2-propanediol

Suppliers and Price of (2R)-2-(3-bromophenyl)-1,2-propanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R)-2-(3-bromophenyl)-1,2-propanediol

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:229.99424
Heavy Atom Count:12
Complexity:152

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(CO)(C1=CC(=CC=C1)Br)O
Isomeric SMILES:C[C@](CO)(C1=CC(=CC=C1)Br)O

Technology Process of (2R)-2-(3-bromophenyl)-1,2-propanediol

There total 4 articles about (2R)-2-(3-bromophenyl)-1,2-propanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 25108-58-1
1-bromo-3-isopropenylbenzene

: 861664-75-7
(R)-2-(3-bromophenyl)propane-1,2-diol

Guidance literature:: With AD-mix β; In water; tert-butyl alcohol; at 4 ℃; for 16h;

Reference yield:

: C₉H₉BrO₂

: 861664-75-7
(R)-2-(3-bromophenyl)propane-1,2-diol

: C₉H₁₁BrO₂

Guidance literature:: With sodium tetrahydroborate; In methanol; at 23 ℃; for 1.5h; Overall yield = 56 %; Overall yield = 3.6 mg;
DOI:10.1021/acs.orglett.5b01193

Reference yield:

: 1257310-91-0
1-bromo-3-(1-methoxyprop-1-en-2-yl)benzene

: 861664-75-7
(R)-2-(3-bromophenyl)propane-1,2-diol

: C₉H₁₁BrO₂

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen bromide / water; acetone / 46 h / 0 - 23 °C

2: N-(4-nitrobenzenesulfonyl)-3,3-dimethyloxaziridine; trifluoroacetic acid; sodium hydrogencarbonate; C₂₅H₂₆N₂O / tetrahydrofuran / 23 °C / Sealed tube

3: sodium tetrahydroborate / methanol / 1.5 h / 23 °C

With sodium tetrahydroborate; N-(4-nitrobenzenesulfonyl)-3,3-dimethyloxaziridine; C₂₅H₂₆N₂O; hydrogen bromide; sodium hydrogencarbonate; trifluoroacetic acid; In tetrahydrofuran; methanol; water; acetone;
DOI:10.1021/acs.orglett.5b01193