2,N-dihydroxy-5-iodo-3-methylbenzamide

Base Information

Chemical Name:2,N-dihydroxy-5-iodo-3-methylbenzamide
CAS No.:864755-98-6
Molecular Formula:C8H8INO3
Molecular Weight:293.061
Hs Code.:
DSSTox Substance ID:DTXSID30468457
Wikidata:Q82295657

Synonyms:2,N-dihydroxy-5-iodo-3-methylbenzamide;864755-98-6;SCHEMBL4869788;DTXSID30468457;DILCFCUOIBZXII-UHFFFAOYSA-N

Suppliers and Price of 2,N-dihydroxy-5-iodo-3-methylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,N-dihydroxy-5-iodo-3-methylbenzamide

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:292.95489
Heavy Atom Count:13
Complexity:200

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1O)C(=O)NO)I

Technology Process of 2,N-dihydroxy-5-iodo-3-methylbenzamide

There total 3 articles about 2,N-dihydroxy-5-iodo-3-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 40912-75-2
2-hydroxy-5-iodo-3-methylbenzoic acid methyl ester

: 864755-98-6
2,N-dihydroxy-5-iodo-3-methylbenzamide

Guidance literature:: With potassium hydroxide; hydroxylamine hydrochloride; In methanol; for 6h; Heating;
DOI:10.1021/jm050452s

Reference yield:

: 83-40-9
3-methylsalicylic acid

: 864755-98-6
2,N-dihydroxy-5-iodo-3-methylbenzamide

Guidance literature:: Multi-step reaction with 3 steps

1: tetrabutylammonium bromide; aq. potassium carbonate / CH₂Cl₂ / 4 h / 20 °C

2: sodium iodide; sodium hydroxide; aq. sodium hypochlorite / methanol / 4.5 h / 0 - 3 °C

3: 84 percent / hydroxylamine hydrochloride; potassium hydroxide / methanol / 6 h / Heating

With potassium hydroxide; sodium hydroxide; sodium hypochlorite; hydroxylamine hydrochloride; tetrabutylammomium bromide; potassium carbonate; sodium iodide; In methanol; dichloromethane;
DOI:10.1021/jm050452s

Reference yield:

: 23287-26-5
3-methylsalicylic acid methyl ester

: 864755-98-6
2,N-dihydroxy-5-iodo-3-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium iodide; sodium hydroxide; aq. sodium hypochlorite / methanol / 4.5 h / 0 - 3 °C

2: 84 percent / hydroxylamine hydrochloride; potassium hydroxide / methanol / 6 h / Heating

With potassium hydroxide; sodium hydroxide; sodium hypochlorite; hydroxylamine hydrochloride; sodium iodide; In methanol;
DOI:10.1021/jm050452s