Benzocyclobutenone

Base Information

• Chemical Name: Benzocyclobutenone
• CAS No.: 3469-06-5
• Molecular Formula: C8H6 O
• Molecular Weight: 118.135
• Hs Code.: 2914390090
• Mol file: 3469-06-5.mol

Synonyms:1-Oxocyclobutabenzene;Benzocyclobutanone; Benzocyclobuten-1(2H)-one; Benzocyclobutenone; NSC 146572

Chemical Property of Benzocyclobutenone

Chemical Property:

• Vapor Pressure: 0.118mmHg at 25°C
• Refractive Index: 1.614
• Boiling Point: 219.6 °C at 760 mmHg
• Flash Point: 85.9 °C
• Density: 1.214 g/cm³
• Storage Temp.: 2-8°C

Purity/Quality:

98%, ^*data from raw suppliers

Benzocyclobuten-1(2h)-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzocyclobutenone

There total 60 articles about Benzocyclobutenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

7,7-Dimethoxybicyclo<4.2.0>octa-1,3,5-triene (81447-53-2) → benzocyclobutenone (3469-06-5)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 2h;

DOI:10.1021/jo00133a031

Reference yield: 100.0%

2-(1'-Hydroxy-1',2'-dihydrobenzocyclobuten-1'-yl)-2,4-dimethylpentan-3-one (126889-57-4) → benzocyclobutenone (3469-06-5)

Guidance literature:

at 150 ℃; for 3h;

DOI:10.1039/c39900000374

Reference yield: 88.0%

C20H17O4P → benzocyclobutenone (3469-06-5)

Guidance literature:

With potassium phosphate; In toluene; at 20 ℃; for 2h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/acs.orglett.8b00160

upstream raw materials:

1,2-dihydrobenzocyclobuten-1-ol

1-bromobenzocyclobutene

maleic anhydride

6-methylene-2,4-cyclohexadienylideneketene

Downstream raw materials:

2-Methyl-benzoic acid methyl ester

7-methylbicyclo[4.2.0]octa-1,3,5-trien-7-ol

1,2-dihydrobenzocyclobuten-1-ol

1-methylenebenzocyclobutane