Chemical Property of Belinostat
Chemical Property:
- Melting Point:172 °C(Solv: ethyl acetate (141-78-6))
- PKA:8.27±0.10(Predicted)
- PSA：107.37000
- Density:1.427±0.06 g/cm3(Predicted)
- LogP:4.00010
- Storage Temp.:Sealed in dry,Room Temperature
- XLogP3:1.7
- Hydrogen Bond Donor Count:3
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:5
- Exact Mass:318.06742811
- Heavy Atom Count:22
- Complexity:492
- Purity/Quality:
-
97% *data from raw suppliers
Belinostat *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
-
SDS file from LookChem
Useful:
- Drug Classes:Antineoplastic Agents
- Canonical SMILES:C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)C=CC(=O)NO
- Isomeric SMILES:C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
- Recent ClinicalTrials:Tremelimumab, Durvalumab, and Belinostat for the Treatment of ARID1A Mutated Metastatic or Unresectable, Locally Advanced Urothelial Carcinoma
- Recent EU Clinical Trials:Randomised Open Label Adaptive Phase III trial of addition of Belinostat to chemotherapy in patients with locally advanced potentially resectable Thymic Epithelial Tumors (TET)
