L-Proline, 1-(1-oxo-4-phenylbutyl)-

Base Information

Chemical Name:L-Proline, 1-(1-oxo-4-phenylbutyl)-
CAS No.:86778-86-1
Molecular Formula:C15H19NO3
Molecular Weight:261.321
Hs Code.:
DSSTox Substance ID:DTXSID50438637
Wikidata:Q82254441

Synonyms:L-Proline, 1-(1-oxo-4-phenylbutyl)-;86778-86-1;SCHEMBL5741647;N-(4-phenylbutyryl)-L-proline;DTXSID50438637;XQIRATUKSYJTKI-ZDUSSCGKSA-N;N-(gamma-phenyl)butyryl-L-proline;AKOS010372134

Suppliers and Price of L-Proline, 1-(1-oxo-4-phenylbutyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of L-Proline, 1-(1-oxo-4-phenylbutyl)-

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:261.13649347
Heavy Atom Count:19
Complexity:323

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(N(C1)C(=O)CCCC2=CC=CC=C2)C(=O)O
Isomeric SMILES:C1C[C@H](N(C1)C(=O)CCCC2=CC=CC=C2)C(=O)O

Technology Process of L-Proline, 1-(1-oxo-4-phenylbutyl)-

There total 8 articles about L-Proline, 1-(1-oxo-4-phenylbutyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 18496-54-3
phenylbutyric acid chloride

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 86778-86-1
N-(4-phenylbutanoyl)-L-proline

Guidance literature:: With sodium hydroxide; at 0 - 4 ℃; for 0.25h;
DOI:10.1016/0223-5234(96)80448-X

Reference yield: 79.0%

: 88105-73-1
N-(4-phenylbutyryl)-L-proline benzyl ester

: 86778-86-1
N-(4-phenylbutanoyl)-L-proline

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 3102.9 Torr;
DOI:10.1021/jm00369a017

Reference yield:

: 18496-54-3
phenylbutyric acid chloride

: 86778-86-1
N-(4-phenylbutanoyl)-L-proline

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / pyridine / CH₂Cl₂ / 3 h / 25 °C

2: 79 percent / H₂ / 10percent Pd/C / ethanol / 3102.9 Torr

With pyridine; hydrogen; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1021/jm00369a017