N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide

Base Information

Chemical Name:N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide
CAS No.:86785-38-8
Molecular Formula:C15H15BrN2O3S
Molecular Weight:383.266
Hs Code.:
DSSTox Substance ID:DTXSID70522209
Wikidata:Q82387282

Synonyms:86785-38-8;DTXSID70522209;N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide

Suppliers and Price of N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:381.99868
Heavy Atom Count:22
Complexity:472

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)NC(=O)CBr)NS(=O)(=O)C2=CC=CC=C2

Technology Process of N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide

There total 3 articles about N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}-2-bromoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 86785-35-5
2'-methyl-4'-aminobenzenesulfonanilide

: 598-21-0
2-Bromoacetyl bromide

: 86785-38-8
2'-methyl-4'-(bromoacetamido)benzenesulfonanilide

Guidance literature:: With potassium hydrogencarbonate; In chloroform; for 24.5h; Ambient temperature;
DOI:10.1021/jo00167a002

Reference yield:

: 86785-33-3
N-(2-methyl)-4-nitrophenylbenzenesulfonamide

: 86785-38-8
2'-methyl-4'-(bromoacetamido)benzenesulfonanilide

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / sodium dithionite / methanol; aq. NH₃ / 1.) 30 min, 2.) refrigerator, 1 h

2: 96 percent / potassium bicarbonate / CHCl₃ / 24.5 h / Ambient temperature

With sodium dithionite; potassium hydrogencarbonate; In methanol; ammonium hydroxide; chloroform;
DOI:10.1021/jo00167a002

Reference yield:

: 99-52-5
2-methyl-4-nitro-benzenamine

: 86785-38-8
2'-methyl-4'-(bromoacetamido)benzenesulfonanilide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / pyridine / 13 h / Ambient temperature

2: 77 percent / sodium dithionite / methanol; aq. NH₃ / 1.) 30 min, 2.) refrigerator, 1 h

3: 96 percent / potassium bicarbonate / CHCl₃ / 24.5 h / Ambient temperature

With pyridine; sodium dithionite; potassium hydrogencarbonate; In methanol; ammonium hydroxide; chloroform;
DOI:10.1021/jo00167a002