N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide

Base Information

Chemical Name:N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide
CAS No.:86822-01-7
Molecular Formula:C15H16N2O3S
Molecular Weight:304.37
Hs Code.:
DSSTox Substance ID:DTXSID00522212
Wikidata:Q82387288

Synonyms:86822-01-7;N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide;DTXSID00522212

Suppliers and Price of N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:304.08816355
Heavy Atom Count:21
Complexity:452

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)NC(=O)C)NS(=O)(=O)C2=CC=CC=C2

Technology Process of N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide

There total 3 articles about N-{4-[(Benzenesulfonyl)amino]-3-methylphenyl}acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 86785-35-5
2'-methyl-4'-aminobenzenesulfonanilide

: 108-24-7
acetic anhydride

: 86822-01-7
2'-methyl-4'-acetamidobenzenesulfonanilide

Guidance literature:: With sodium acetate; In acetic acid;
DOI:10.1021/jo00167a002

Reference yield:

: 86785-33-3
N-(2-methyl)-4-nitrophenylbenzenesulfonamide

: 86822-01-7
2'-methyl-4'-acetamidobenzenesulfonanilide

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / sodium dithionite / methanol; aq. NH₃ / 1.) 30 min, 2.) refrigerator, 1 h

2: 93 percent / sodium acetate / acetic acid

With sodium dithionite; sodium acetate; In methanol; ammonium hydroxide; acetic acid;
DOI:10.1021/jo00167a002

Reference yield:

: 99-52-5
2-methyl-4-nitro-benzenamine

: 86822-01-7
2'-methyl-4'-acetamidobenzenesulfonanilide

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / pyridine / 13 h / Ambient temperature

2: 77 percent / sodium dithionite / methanol; aq. NH₃ / 1.) 30 min, 2.) refrigerator, 1 h

3: 93 percent / sodium acetate / acetic acid

With pyridine; sodium dithionite; sodium acetate; In methanol; ammonium hydroxide; acetic acid;
DOI:10.1021/jo00167a002