Taniplon

Base Information

Chemical Name:Taniplon
CAS No.:106073-01-2
Molecular Formula:C₁₄H₁₅N₅O₂
Molecular Weight:285.305
Hs Code.:
UNII:OKS0I0BBLP
DSSTox Substance ID:DTXSID00147500
Nikkaji Number:J409.299F
Wikipedia:Taniplon
Wikidata:Q7683321
NCI Thesaurus Code:C76947
ChEMBL ID:CHEMBL66648
Mol file:106073-01-2.mol

Synonyms:Taniplon;106073-01-2;Taniplon [INN];OKS0I0BBLP;UNII-OKS0I0BBLP;3-(5-methoxy-6,7,8,9-tetrahydroimidazo[1,2-a]quinazolin-2-yl)-5-methyl-1,2,4-oxadiazole;CHEMBL66648;SCHEMBL2111066;DTXSID00147500;RU-33543;Q7683321;6,7,8,9-Tetrahydro-5-methoxy-2-(5-methyl-1,2,4-oxadiazol-3-yl)imidazo-(1,2-a)-quinazoline

Suppliers and Price of Taniplon

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TANIPLON 95.00%
5MG
$ 505.27

Total 3 raw suppliers

Chemical Property of Taniplon

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：78.34000
Density:1.54g/cm³
LogP:1.97510
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:285.12257474
Heavy Atom Count:21
Complexity:384

Purity/Quality:

98%min ^*data from raw suppliers

TANIPLON 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=NO1)C2=CN3C4=C(CCCC4)C(=NC3=N2)OC

Technology Process of Taniplon

There total 9 articles about Taniplon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90808-73-4
4-Methoxy-5,6,7,8-tetrahydro-quinazolin-2-ylamine

: 106073-01-2
6,7,8,9-tetrahydro-5-methoxy-2-(5-methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]quinazoline

Guidance literature:: Multi-step reaction with 7 steps

1: 1.) ether, RT, 24 h, 2.) ethanol, reflux, 2 h

2: K₂CO₃ / methanol; H₂O / 2 h / Heating

3: dimethylformamide / 2 h / Ambient temperature

4: NH₃ / CHCl₃ / Ambient temperature

5: triethylamine, trifluoroacetic anhydride / CH₂Cl₂ / 0.33 h / Ambient temperature

6: hydroxylamine hydrochloride, KOH / ethanol / 4.5 h / Heating

7: 1 h / 100 °C

With potassium hydroxide; hydroxylamine hydrochloride; ammonia; potassium carbonate; triethylamine; trifluoroacetic anhydride; In methanol; ethanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00111a021

Reference yield:

: 133602-78-5
ethyl 5-methoxy-6,7,8,9-tetrahydroimidazo<1,2-a>quinazoline-2-carboxylate

: 106073-01-2
6,7,8,9-tetrahydro-5-methoxy-2-(5-methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]quinazoline

Guidance literature:: Multi-step reaction with 6 steps

1: K₂CO₃ / methanol; H₂O / 2 h / Heating

2: dimethylformamide / 2 h / Ambient temperature

3: NH₃ / CHCl₃ / Ambient temperature

4: triethylamine, trifluoroacetic anhydride / CH₂Cl₂ / 0.33 h / Ambient temperature

5: hydroxylamine hydrochloride, KOH / ethanol / 4.5 h / Heating

6: 1 h / 100 °C

With potassium hydroxide; hydroxylamine hydrochloride; ammonia; potassium carbonate; triethylamine; trifluoroacetic anhydride; In methanol; ethanol; dichloromethane; chloroform; water; N,N-dimethyl-formamide;
DOI:10.1021/jm00111a021