4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline

Base Information

Chemical Name:4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline
CAS No.:87114-17-8
Molecular Formula:C₁₈H₁₆N₂
Molecular Weight:260.338
Hs Code.:
DSSTox Substance ID:DTXSID101200365

Synonyms:87114-17-8;4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline;DTXSID101200365

Suppliers and Price of 4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:260.131348519
Heavy Atom Count:20
Complexity:336

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=NN2C(C3=CC=CC=C3CC2=C1)C4=CC=CC=C4

Technology Process of 4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline

There total 2 articles about 4,9-Dihydro-2-methyl-9-phenylpyrazolo[1,5-b]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 463-51-4
Ketene

: 87101-42-6
(2-((diphenylmethylene)hydrazono)propylidene)triphenylphosphorane

: 87114-17-8
2-methyl-9-phenyl-4,9-dihydropyrazolo<1,5-b>isoquinoline

Guidance literature:: In benzene; 1.) room temp., 0.5 h, 2.) reflux, 26 h;
DOI:10.1021/jo00170a004

Reference yield:

: 87101-39-1
2-((diphenylmethylene)hydrazono)propyltriphenylphosphonium bromide

: 87114-17-8
2-methyl-9-phenyl-4,9-dihydropyrazolo<1,5-b>isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / potassium hydroxide / ethanol / 1.) -15 deg C, 2.) room temp., 30 min

2: 74 percent / benzene / 1.) room temp., 0.5 h, 2.) reflux, 26 h

With potassium hydroxide; In ethanol; benzene;
DOI:10.1021/jo00170a004