trans-4-(trans-4-Propylcyclohexyl)cyclohexanol

Base Information

• Chemical Name: trans-4-(trans-4-Propylcyclohexyl)cyclohexanol
• CAS No.: 87144-93-2
• Molecular Formula: C15H28O
• Molecular Weight: 224.387
• European Community (EC) Number: 617-390-9
• DSSTox Substance ID: DTXSID501002939
• Nikkaji Number: J1.925.234E
• Mol file: 87144-93-2.mol

Synonyms:82832-72-2;TRANS-4-(TRANS-4-PROPYLCYCLOHEXYL)CYCLOHEXANOL;(trans,trans)-4'-Propyl-[1,1'-bi(cyclohexan)]-4-ol;4-(4-propylcyclohexyl)cyclohexan-1-ol;MFCD09752068;4'-propyl-1,1'-bi(cyclohexyl)-4-ol;4'-Propyl-bicyclohexyl-4-ol;4-(4-propylcyclohexyl)cyclohexanol;SCHEMBL2784619;SCHEMBL2784623;SCHEMBL3247418;SCHEMBL9648978;SCHEMBL9648985;SCHEMBL15725329;DFXWFFHIZJDOFZ-KTSLABGISA-N;DFXWFFHIZJDOFZ-UHFFFAOYSA-N;DTXSID501002939;STK065378;AKOS000618763;AKOS015918015;AKOS016009394;AKOS024438127;DS-5483;SB66684;4'-propyl-4-hydroxy-1,1'-bicyclohexane;SY113156;4'-Propyl[1,1'-bi(cyclohexane)]-4-ol;CS-0152582;FT-0689197;P2434;F16532;A864333;4'alpha-Propyl-1alpha,1'beta-bi[cyclohexane]-4beta-ol

Chemical Property of trans-4-(trans-4-Propylcyclohexyl)cyclohexanol

Chemical Property:

• XLogP3: 5.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 224.214015512
• Heavy Atom Count: 16
• Complexity: 186

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC1CCC(CC1)C2CCC(CC2)O

Technology Process of trans-4-(trans-4-Propylcyclohexyl)cyclohexanol

There total 1 articles about trans-4-(trans-4-Propylcyclohexyl)cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

biphenyl (92-52-4,1594-86-1) → 4-(4-propylcyclohexyl)-cyclohexanol (87144-93-2)

Guidance literature:

Multi-step reaction with 5 steps

1: aluminum (III) chloride / dichloromethane / 4 h / 10 - 20 °C

2: zinc(II) chloride / dichloromethane / 10 h / 0 - 20 °C

3: hydrogen; palladium/alumina / methanol / 24 h / 20 °C / 7500.75 Torr

4: oxygen; sodium carbonate / toluene / 10 h / 110 °C / 37503.8 Torr

5: hydrogen; Rh/SiO₂ / ethanol / 5 h / 80 °C / 37503.8 Torr

With aluminum (III) chloride; Rh/SiO₂; palladium/alumina; hydrogen; oxygen; sodium carbonate; zinc(II) chloride; In methanol; ethanol; dichloromethane; toluene; 2: |Friedel-Crafts Alkylation;

Reference yield: 89.0%

4-(4-propylcyclohexyl)-cyclohexanol (87144-93-2) → trans-4-(4-n-propylcyclohexyl)cyclohexanone (87625-09-0)

Guidance literature:

4-(4-propylcyclohexyl)-cyclohexanol; With 4-hydroxy-2,2,6,6-tetramethylpiperidinyl-1-oxyl anion; In 1,2-dichloro-ethane; at 5 ℃; for 0.25h;

With trichloroisocyanuric acid; In 1,2-dichloro-ethane; for 8h;

Reference yield: 81.0%

4-formylbenzoyl chloride (16173-52-7) + 4-(4-propylcyclohexyl)-cyclohexanol (87144-93-2) → C23H32O3

Guidance literature:

With triethylamine;

DOI:10.1080/15421406.2011.569689

upstream raw materials:

biphenyl

Downstream raw materials:

trans-4-(4-n-propylcyclohexyl)cyclohexanone

Refernces