2-Oxa-5-azabicyclo[2.2.2]octan-6-one, 8-(acetyloxy)-3-[(S)-(acetyloxy)[(4R)-2-phenyl-1,3-dioxolan-4-yl]methyl]- 1-(phenylthio)-, (1S,3R,4R,8S)-

Base Information

Chemical Name:2-Oxa-5-azabicyclo[2.2.2]octan-6-one, 8-(acetyloxy)-3-[(S)-(acetyloxy)[(4R)-2-phenyl-1,3-dioxolan-4-yl]methyl]- 1-(phenylthio)-, (1S,3R,4R,8S)-
CAS No.:872120-65-5
Molecular Formula:C26H27NO8S
Molecular Weight:513.568
Hs Code.:

Synonyms:

Suppliers and Price of 2-Oxa-5-azabicyclo[2.2.2]octan-6-one, 8-(acetyloxy)-3-[(S)-(acetyloxy)[(4R)-2-phenyl-1,3-dioxolan-4-yl]methyl]- 1-(phenylthio)-, (1S,3R,4R,8S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Oxa-5-azabicyclo[2.2.2]octan-6-one, 8-(acetyloxy)-3-[(S)-(acetyloxy)[(4R)-2-phenyl-1,3-dioxolan-4-yl]methyl]- 1-(phenylthio)-, (1S,3R,4R,8S)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Oxa-5-azabicyclo[2.2.2]octan-6-one, 8-(acetyloxy)-3-[(S)-(acetyloxy)[(4R)-2-phenyl-1,3-dioxolan-4-yl]methyl]- 1-(phenylthio)-, (1S,3R,4R,8S)-

There total 7 articles about 2-Oxa-5-azabicyclo[2.2.2]octan-6-one, 8-(acetyloxy)-3-[(S)-(acetyloxy)[(4R)-2-phenyl-1,3-dioxolan-4-yl]methyl]- 1-(phenylthio)-, (1S,3R,4R,8S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 872120-63-3
methyl (phenyl 8,9-O-benzylidene-3,5-dideoxy-2-thio-5-trifluoroacetamido-D-glycero-α-D-galacto-2-nonulopyranosid)onate

: 108-24-7
acetic anhydride

: 872120-65-5
phenyl 4,7-di-O-acetyl-5-amino-9-O-benzylidene-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranoside-1,5-lactam

Guidance literature:: methyl (phenyl 8,9-O-benzylidene-3,5-dideoxy-2-thio-5-trifluoroacetamido-D-glycero-α-D-galacto-2-nonulopyranosid)onate; With calcium sulfate; sodium methylate; In methanol; for 120h; Heating;

acetic anhydride; With dmap; In pyridine; for 3h;

With hydrazinium monoacetate; In tetrahydrofuran; at 20 ℃; for 1.33333h;
DOI:10.1016/j.carres.2006.03.017

Reference yield:

: Acetic acid (1S,3R,4R,8S)-3-[(S)-acetoxy-((R)-2-phenyl-[1,3]dioxolan-4-yl)-methyl]-5-acetyl-6-oxo-1-phenylsulfanyl-2-oxa-5-aza-bicyclo[2.2.2]oct-8-yl ester

: 872120-65-5
phenyl 4,7-di-O-acetyl-5-amino-9-O-benzylidene-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranoside-1,5-lactam

Guidance literature:: With hydrazinium monoacetate; In tetrahydrofuran; at 20 ℃; for 1.33333h;
DOI:10.1002/anie.200501608

Reference yield:

: methyl (phenyl 3,5-dideoxy-2-thio-5-trifluoroacetamido-D-glycero-α-D-galacto-nonulopyranosid)onate

: 872120-65-5
phenyl 4,7-di-O-acetyl-5-amino-9-O-benzylidene-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranoside-1,5-lactam

Guidance literature:: Multi-step reaction with 4 steps

1: 230 mg / camphorsulfonic acid / dimethylformamide / 2 h / 40 °C

2: 89 percent / sodium methoxide; Drierite / methanol / 120 h / Heating

3: pyridine; 4-dimethylaminopyridine / 3 h / 20 °C

4: 1.38 g / hydrazinium acetate / tetrahydrofuran / 1.33 h / 20 °C

With pyridine; dmap; calcium sulfate; camphor-10-sulfonic acid; sodium methylate; hydrazinium monoacetate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1002/anie.200501608