Hymenoxin

Base Information

Chemical Name:Hymenoxin
CAS No.:56003-01-1
Molecular Formula:C19H18 O8
Molecular Weight:374.347
Hs Code.:
NSC Number:655980
DSSTox Substance ID:DTXSID90204575
Nikkaji Number:J94.522F
Wikidata:Q83078013
Metabolomics Workbench ID:24560
ChEMBL ID:CHEMBL504325
Mol file:56003-01-1.mol

Synonyms:2-(3,4-dimethoxyphenyl)-5,7-dihydroxy-6,8-dimethoxy-4H-chromen-4-one;hymenoxin

Suppliers and Price of Hymenoxin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Hymenoxin

Chemical Property:

Vapor Pressure:1.55E-16mmHg at 25°C
Boiling Point:631.4°Cat760mmHg
Flash Point:228.8°C
PSA：107.59000
Density:1.375g/cm³
LogP:2.90560
XLogP3:2.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:5
Exact Mass:374.10016753
Heavy Atom Count:27
Complexity:564

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)O)OC)O)OC

Technology Process of Hymenoxin

There total 21 articles about Hymenoxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: C₂₁H₂₀O₉

: 56003-01-1
5,7-dihydroxy-6,8,3’,4’-tetramethoxyflavone

Guidance literature:: With potassium carbonate; In methanol;
DOI:10.1016/j.tetlet.2018.03.064

Reference yield:

: C₂₂H₂₂O₉

: 56003-01-1
5,7-dihydroxy-6,8,3’,4’-tetramethoxyflavone

Guidance literature:: Multi-step reaction with 2 steps

1: aluminum (III) chloride; ethanethiol / dichloromethane / 0 - 20 °C

2: potassium carbonate / methanol

With aluminum (III) chloride; potassium carbonate; ethanethiol; In methanol; dichloromethane;
DOI:10.1016/j.tetlet.2018.03.064

Reference yield:

: 30225-99-1
2,3,4,5-Tetramethoxyphenol

: 56003-01-1
5,7-dihydroxy-6,8,3’,4’-tetramethoxyflavone

Guidance literature:: Multi-step reaction with 9 steps

1: potassium carbonate / acetone / 36 h / 20 °C / Inert atmosphere

2: aluminum (III) chloride / dichloromethane / 1 h / 0 - 20 °C

3: lithium chloride / N,N-dimethyl-formamide / 18 h / 120 °C

4: potassium carbonate / N,N-dimethyl-formamide / 3 h / 20 °C

5: lithium hexamethyldisilazane / tetrahydrofuran / 2.5 h / -30 - 0 °C / Inert atmosphere

6: toluene-4-sulfonic acid / toluene / 6 h / 20 - 80 °C

7: dmap / pyridine / 0.5 h / 20 °C

8: aluminum (III) chloride / dichloromethane / 2 h / 0 - 20 °C

9: potassium carbonate / methanol / 3 h / 20 °C

With dmap; aluminum (III) chloride; potassium carbonate; toluene-4-sulfonic acid; lithium chloride; lithium hexamethyldisilazane; In tetrahydrofuran; pyridine; methanol; dichloromethane; N,N-dimethyl-formamide; acetone; toluene; 2: |Friedel-Crafts Acylation;
DOI:10.1021/acs.oprd.9b00091