6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one

Base Information Edit

Chemical Name:6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one
CAS No.:19492-02-5
Molecular Formula:C10H7 Cl O3
Molecular Weight:210.61
Hs Code.:2932209090
European Community (EC) Number:832-456-9
DSSTox Substance ID:DTXSID20418744
Nikkaji Number:J2.394.155D
Wikidata:Q27467669
Metabolomics Workbench ID:74107
ChEMBL ID:CHEMBL2205240
Mol file:19492-02-5.mol

Synonyms:6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one;19492-02-5;6-chloro-7-hydroxy-4-methylcoumarin;6-chloro-7-hydroxy-4-methylchromen-2-one;CHEMBL2205240;6-chlor-4-methyl-7-hydroxy-cumarin;MFCD00816527;2H-1-Benzopyran-2-one,6-chloro-7-hydroxy-4-methyl-;XZZ;Oprea1_247174;Oprea1_602281;SCHEMBL2552748;DTXSID20418744;JTXAGHXRIBLWES-UHFFFAOYSA-N;4-Methyl-6-chloro-7-hydroxycoumarin;BBL029037;BDBM50555098;s5760;STK991554;AKOS000522583;AS-68431;PD098319;HY-128416;C3319;CS-0099278;FT-0705119;EN300-10318;T70505;2H-Chromen-2-one, 6-chloro-7-hydroxy-4-methyl-;6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one #;AN-829/25042006;Q27467669;Z57000606;6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one, AldrichCPR

Suppliers and Price of 6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-4-methylumbelliferone
5g
$ 1075.00

TCI Chemical
6-Chloro-7-hydroxy-4-methylcoumarin >98.0%(GC)
5g
$ 464.00

TCI Chemical
6-Chloro-7-hydroxy-4-methylcoumarin >98.0%(GC)
1g
$ 134.00

Matrix Scientific
6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one
500mg
$ 237.00

Crysdot
6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one 97%
5g
$ 752.00

Chem-Impex
6-Chloro-7-hydroxy-4-methylcoumarin,≥98%(GC) ≥98%(GC)
1G
$ 160.28

Chemenu
6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one 97%
5g
$ 711.00

Biosynth Carbosynth
6-Chloro-7-hydroxy-4-methylcoumarin
2 g
$ 250.00

Biosynth Carbosynth
6-Chloro-7-hydroxy-4-methylcoumarin
1 g
$ 150.00

Biosynth Carbosynth
6-Chloro-7-hydroxy-4-methylcoumarin
500 mg
$ 87.50

Total 7 raw suppliers

Chemical Property of 6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one Edit

Chemical Property:

Vapor Pressure:1.35E-06mmHg at 25°C
Melting Point:278 °C
Boiling Point:388.7°Cat760mmHg
Flash Point:188.9°C
PSA：50.44000
Density:1.447g/cm³
LogP:2.46040
Solubility.:soluble in Dimethylformamide
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:210.0083718
Heavy Atom Count:14
Complexity:287

Purity/Quality:

98%,99%, ^*data from raw suppliers

6-Chloro-4-methylumbelliferone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=O)OC2=CC(=C(C=C12)Cl)O
Uses 6-Chloro-4-methylumbelliferone is a fluorescent compound and its excitation and emission can be measured at 361 and 445 nm, respectively. It is used to develop novel fluorogenic substrates for the β-glycosidase assay.

Technology Process of 6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one

There total 5 articles about 6-Chloro-7-hydroxy-4-methyl-2H-chromen-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 95-88-5
4-Chlororesorcinol

: 141-97-9
ethyl acetoacetate

: 19492-02-5
6-chloro-7-hydroxy-4-methyl-2H-chromen-2-one

Guidance literature:: With trifluoroacetic acid; at 100 ℃; for 0.5h; regioselective reaction; Microwave irradiation;
DOI:10.1002/chem.201201039