Technology Process of Oxiranecarboxamide,
N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-2-(phenylmethyl)-,
(2S)-
There total 3 articles about Oxiranecarboxamide,
N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-2-(phenylmethyl)-,
(2S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
for 48h;
Heating;
DOI:10.1021/jm050790t
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-hydroxybenzotriazole; N-methylmorpholine / ethyl acetate / 0.5 h / 20 °C
1.2: 68 percent / ethyl acetate / 20 °C
2.1: 0.414 g / 3-chloroperoxybenzoic acid / CH2Cl2 / 48 h / Heating
With
4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; ethyl acetate;
DOI:10.1021/jm050790t
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-hydroxybenzotriazole; N-methylmorpholine / ethyl acetate / 0.5 h / 20 °C
1.2: 68 percent / ethyl acetate / 20 °C
2.1: 0.414 g / 3-chloroperoxybenzoic acid / CH2Cl2 / 48 h / Heating
With
4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; ethyl acetate;
DOI:10.1021/jm050790t