1-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid

Base Information

Chemical Name:1-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid
CAS No.:872991-72-5
Molecular Formula:C17H25NO2
Molecular Weight:275.391
Hs Code.:
DSSTox Substance ID:DTXSID70403483
Mol file:872991-72-5.mol

Synonyms:872991-72-5;1-(4-TERT-BUTYLBENZYL)PIPERIDINE-4-CARBOXYLIC ACID;1-[(4-tert-butylphenyl)methyl]piperidine-4-carboxylic Acid;1-(4-(tert-Butyl)benzyl)piperidine-4-carboxylic acid;N-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid;SCHEMBL5791973;DTXSID70403483;MFCD05169754;AKOS009484228;1-(4-(tert-Butyl)benzyl)piperidine-4-carboxylicacid;1-(4-tert-butyl-benzyl)-piperidine-4-carboxylic acid

Suppliers and Price of 1-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-(tert-Butyl)benzyl)piperidine-4-carboxylicacid 97%
5g
$ 460.00

American Custom Chemicals Corporation
N-(4-TERT-BUTYLBENZYL)PIPERIDINE-4-CARBOXYLIC ACID 95.00%
5MG
$ 505.97

Total 4 raw suppliers

Chemical Property of 1-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid

Chemical Property:

PSA：40.54000
LogP:3.21860
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:275.188529040
Heavy Atom Count:20
Complexity:318

Purity/Quality:

97% ^*data from raw suppliers

1-(4-(tert-Butyl)benzyl)piperidine-4-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC=C(C=C1)CN2CCC(CC2)C(=O)O

Technology Process of 1-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid

There total 1 articles about 1-(4-Tert-butylbenzyl)piperidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 498-94-2
isonipecotic acid

: 939-97-9
4-tert-Butylbenzaldehyde

: 872991-72-5
1-[4-(1,1-dimethylethyl)phenylmethyl]-4-piperidinecarboxylic acid

Guidance literature:: isonipecotic acid; 4-tert-Butylbenzaldehyde; With sodium tris(acetoxy)borohydride; In 1,1-dichloroethane;

With water; In 1,1-dichloroethane; for 0.166667h;

Reference yield: 23.0%

: 872991-72-5
1-[4-(1,1-dimethylethyl)phenylmethyl]-4-piperidinecarboxylic acid

: 872991-71-4
3-fluoro-4-(4-morpholinyl)-N-(tetrahydro-2H-pyran-4-ylmethyl)aniline

: 1-[4-(1,1-dimethylethyl)phenyl]methyl-N-[3-fluoro-4-(4-morpholinyl)phenyl]-N-(tetrahydro-2H-pyran-4-ylmethyl)-4-piperidinecarboxamide

Guidance literature:: 1-[4-(1,1-dimethylethyl)phenylmethyl]-4-piperidinecarboxylic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; for 4h;

3-fluoro-4-(4-morpholinyl)-N-(tetrahydro-2H-pyran-4-ylmethyl)aniline; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃;

With PS-Trisamine scavenger reagent; In dichloromethane; for 20h;