5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid

Base Information

Chemical Name:5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid
CAS No.:1195-19-3
Molecular Formula:C₅H₇NO₄
Molecular Weight:145.115
Hs Code.:
NSC Number:143122
DSSTox Substance ID:DTXSID70301399
Nikkaji Number:J3.497.089K
Mol file:1195-19-3.mol

Synonyms:1195-19-3;5-methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid;5-Methyl-2-oxooxazolidine-4-carboxylic acid;4-Oxazolidinecarboxylic acid, 5-methyl-2-oxo-;NSC143122;SCHEMBL2707859;DTXSID70301399;BAA19519;4-carboxy-5-methyl-oxazolidin-2-one;AKOS006357939;NSC-143122;5-Methyl-2-oxooxazolidine-4-carboxylicacid;CS-0530438;EN300-172640;Z1203735062

Suppliers and Price of 5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid

Chemical Property:

Vapor Pressure:3.67E-11mmHg at 25°C
Boiling Point:495.3°Cat760mmHg
Flash Point:253.4°C
Density:1.388g/cm³
XLogP3:-0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:145.03750770
Heavy Atom Count:10
Complexity:179

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(NC(=O)O1)C(=O)O

Technology Process of 5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid

There total 15 articles about 5-Methyl-2-oxo-1,3-oxazolidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 119221-16-8
(2R,3R)-2-(benzyloxycarbonylamino)-3-hydroxybutanoic acid

: 1195-19-3,1195-20-6,37791-36-9,50896-26-9,98302-45-5,122871-70-9
(4R,5R)-5-methyl-2-oxooxazolidine-4-carboxylic acid

Guidance literature:: With sodium hydroxide; In methanol; water; for 3.75h; Cooling with ice;
DOI:10.1002/psc.3228

Reference yield:

: 72-19-5,134357-96-3,7013-32-3,82822-12-6
L-threonine

: 1195-19-3,1195-20-6,37791-36-9,50896-26-9,98302-45-5,122871-70-9
(4R,5R)-5-methyl-2-oxooxazolidine-4-carboxylic acid

Guidance literature:: With hydrogenchloride; In water; pH=1;

Reference yield:

: 37791-40-5
N-benzoyl-O-chlorocarbonyl-DL-threonine benzyl ester

: 1195-19-3,1195-20-6,37791-36-9,50896-26-9,98302-45-5,122871-70-9
DL-trans-5-Methyl-2-oxo-oxazolidin-4-carbonsaeure

Guidance literature:: Multi-step reaction with 5 steps

1: xylene / 2 h / Heating

2: H₂ / Pd-C / methanol; H₂O

3: SOCl₂ / benzene

5: KOH / methanol / 3.5 h / Ambient temperature

With potassium hydroxide; thionyl chloride; hydrogen; palladium on activated charcoal; In methanol; water; xylene; benzene;
DOI:10.1246/bcsj.45.1254